COVID-19 updates: LA has highest daily death total since April

There are over 4,300 people hospitalized with COVID-19 in Los Angeles County.

As the COVID-19 pandemic has swept the globe, more than 5.5 million people have died from the disease worldwide, including over 849,000 Americans, according to real-time data compiled by Johns Hopkins University's Center for Systems Science and Engineering.

About 62.9% of the population in the United States is fully vaccinated against COVID-19, according to data from the Centers for Disease Control and Prevention.


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Maine, Massachusetts activate more National Guard members

Massachusetts Gov. Charlie Baker said he's activating 500 more National Guard members to support the state's strained health care system.

Baker had activated 250 National Guard members when students returned to classrooms in the fall to help with school transportation, ABC Boston affiliate WCVB reported.

In Maine, Gov. Janet Mills is activating up to 169 National Guard members to help overrun hospitals, ABC affiliate WMTW reported. Maine hit a hospitalization record Monday with over 400 COVID-19 patients in hospitals, according to WMTW.


New Orleans reinstates mask mandate ahead of Mardi Gras

New Orleans will reinstate its indoor mask mandate beginning Wednesday as the city gears up for Mardi Gras celebrations.

Masks will be required in restaurants, bars, gyms, entertainment venues and public transportation.

About 64.6% of New Orleans residents are fully vaccinated, according to the city.

People 5 and older must show proof of vaccination or a negative test to access indoor restaurants, bars, entertainment venues, bowling alleys, indoor playgrounds, arcades and similar settings.


Omicron estimated to account for 98% of new US cases: CDC

Omicron is estimated to account for 98.3% of new cases in the U.S. as of Jan. 8, according to new data released by CDC Tuesday. (These figures are calculated using modeling and may not be exact.)

Delta now accounts for only 1.7% of new cases nationally, forecasters estimate.

In three areas of the country -- the deep South, the Southeast and the New York/New Jersey region -- omicron is estimated to account for more than 99% of new cases.

In early December, omicron was estimated to account for just 0.6% of all new cases.

-ABC News' Arielle Mitropoulos


White House limiting gatherings to 30 people due to omicron

The White House has been limiting its in-person gatherings to 30 people "over the last several weeks" due to the omicron surge, White House press secretary Jen Psaki said.

“We wear masks in the West Wing at all times, including in your office, unless you're in your office alone,” Psaki said.

-ABC News' Ben Gittleson


More than 15 million new cases reported globally last week

More than 15 million new COVID-19 cases were reported globally last week, according to the World Health Organization.

"By far the most cases reported in a single week, and we know this is an underestimate," WHO Director-General Dr. Tedros Adhanom Ghebreyesus said Wednesday.

He said this "huge spike" is driven by omicron.

"While omicron causes less severe disease than delta, it remains a dangerous virus, particularly for those who are unvaccinated," Tedros warned.

WHO officials said new vaccines may be needed for different variants, and until those vaccines are developed, the current vaccines may need to be updated.

-ABC News' Christine Theodorou