Vaccine appointments in New York City will be rescheduled due to a major winter storm heading toward the East Coast.

The nor'easter is expected to begin Sunday night and could dump up to a foot of snow onto the city.

"Last thing we want to do is to urge our seniors to come out in the middle of a storm like this," NYC Mayor Bill de Blasio said at a press conference Sunday morning. "It doesn't make sense."

-ABC News' Joshua Hoyos

The mass COVID-19 vaccination site at Dodger Stadium, one of the largest in the country, was temporarily halted Saturday after the entrance was blocked by anti-vaccine protesters.

The group carried anti-vaccine and anti-mask signs, leading to a long line of cars waiting to get into the stadium, ABC Los Angeles station KABC reported.

The stadium entrance was closed from about 1:50 p.m. to 2:45 p.m., Los Angeles Fire Department Public Information Officer David Ortiz told ABC News. Vaccinations continued inside as the gate was closed, Ortiz said.

A social media post described the demonstration as "SCAMDEMIC PROTEST/MARCH" and advised participants to refrain from wearing pro-Trump or MAGA attire.

"…we want our statement to resonate with the sheeple," the post read, according to The Associated Press. “No flags but informational signs only.”

No arrests were made as a result of the protests.

Republican Arkansas Gov. Asa Hutchinson said Sunday that vaccine distribution has been "seamless" under the Biden administration.

"In terms of the vaccine distribution, it's been seamless. And I was delighted that we had a ... 14% increase in vaccine supply last week. This is going to be very, very important for us. They said they're going to invoke the Defense Production Act. I don't know the details on that, but anything they can do to speed up the production," Hutchinson said on ABC's "This Week."

"Thank goodness we have that partnership which is good with the federal government. And President Biden and his team is -- is working to assure that partnership and not tear it apart, which I'm very grateful for," he told "This Week" Co-anchor Martha Raddatz.

-ABC News' Jack Arnholz

Dave McGillivray, the race director of the Boston Marathon, has been selected by the state of Massachusetts to run the mass vaccination operations at Gillette Stadium and Fenway Park.

McGillivray owns DMSE Sports, which organizes and manages dozens of outdoor events every year. To help keep DMSE Sports afloat, McGillivray connected with CIC Health -- which operates the mass COVID-19 vaccination sites at Fenway Park and Gillette Stadium -- through the state of Massachusetts.

Now, McGillivray is running logistics for both sites.

"For me, the feeling is so good that the thing that knocked us to our knees is now the thing that is allowing us to do good: that we're keeping people healthy, we're saving lives and we're even bringing our own industry back," McGillivray said in an interview with Boston ABC affiliate WCVB().

Fenway Park is the home of the Boston Red Sox, while Gillette Stadium, located in Foxborough, is the home stadium for the New England Patriots. The Gillette Stadium site opened two weeks ago, with Fenway officially opening Monday. Both sites are expected to administer 5,000 doses per day once fully up and running.

The Boston Marathon, usually held in April, has been postponed to October. The in-person event was canceled in 2020, though it was held virtually.

ABC News' Arielle Mitropoulos contributed to this report.

COVID-19 cases and deaths are surging across Africa as new, more contagious variants of the novel coronavirus spread to additional countries, the World Health Organization warned Thursday.

"The variant which was first detected in South Africa has spread quickly beyond Africa and so what’s keeping me awake at night right now is that it’s very likely circulating in a number of African countries," Dr. Matshidiso Moeti, the WHO's regional director for Africa, said in a statement.

Diagnosed COVID-19 infections increased by 50% in Africa between Dec. 29 and Jan. 25, when compared with the previous four weeks. Deaths from the disease rose two-fold in the same period, with over 15,000 concentrated in 10 mainly southern and northern African nations, according to the WHO.

Over the last week, more than 175,000 new cases and over 6,200 new deaths were reported across the continent. There was a small dip in cases in South Africa, but 22 countries continue to see their numbers surge, according to the WHO.

The B1351 variant, first identified in South Africa, is "predominant and powering record case numbers in South Africa and the sub-region," the WHO said. The strain has been detected in Botswana, Ghana, Kenya, the French Indian Ocean region of Mayotte, Zambia and at least 24 non-African nations, according to the WHO.

Meanwhile, another new, highly contagious variant called B117, which was initially detected in the United Kingdom, has been found in Gambia and Nigeria.

The WHO said it is working to track and tackle new strains of the deadly virus. The U.N. agency, along with the Africa Centers for Disease Control and Prevention, has helped set up a COVID-19 genomic sequencing laboratory network with labs in the Democratic Republic of the Congo, Gambia, Ghana, Kenya, Nigeria, Senegal, South Africa and Uganda.

"In addition to the new variants, COVID-19 fatigue, and the aftermath of year-end gatherings risk powering a perfect storm and driving up Africa’s second wave and overwhelming health facilities," Moeti said. "Africa is at a crossroads. We must stick to our guns and double down on the tactics we know work so well. That is mask wearing, handwashing and safe social distancing. Countless lives depend on it."