The number of people who have died from COVID-19 in the United States surpassed 800,000 on Tuesday, according to real-time data compiled by Johns Hopkins University's Center for Systems Science and Engineering.

The figure is greater than the approximately 700,000 Americans who have died from AIDS-related illnesses over the last four decades, and it's higher than the total number of U.S. troops who have fallen in battle since 1900.

Since last December, when the first COVID-19 vaccines were being administered, an additional 500,000 people in the U.S. have died from the virus.

Of those, some 230,000 have died since April 2021, when U.S. President Joe Biden announced COVID-19 vaccines were widely available to every American over the age of 18.

-ABC News' Arielle Mitropoulos

The U.S. saw a sevenfold increase in the prevalence of the omicron COVID-19 variant over the last week, according to data from the U.S. Centers for Disease Control and Prevention.

Just over two weeks after it was first discovered in the country, the omicron variant is now estimated to account for nearly 3% of all new cases in the U.S., the latest data from the CDC shows.

Last week, omicron accounted for an estimated 0.4% of all new cases, according to the data.

-ABC News' Arielle Mitropoulos

Dr. Anthony Fauci told CNN Tuesday that omicron will "for sure" become the dominant strain in the U.S. given how rapidly it is spreading.

"Omicron is going to be a challenge because it spreads very rapidly," Fauci said.

Fauci reiterated that omicron so far appears to be less severe, adding, "Whether it is inherently less pathogenic as a virus or whether there is more protection in the community, we're just going to have to see when it comes in the United States."

-ABC News' Arielle Mitropoulos

Cornell University is moving into a "level red" alert after a "significant" number of suspected omicron cases were detected among student samples.

"While we must await confirmatory sequencing information to be sure that the source is Omicron, we are proceeding as if it is," university president Martha Pollack wrote in a letter to the community.

All final exams will be online beginning Tuesday, Pollack announced, and libraries and fitness centers are closed.

All undergraduate events are canceled, as is Saturday's recognition ceremony for December graduates, Pollack said.

Cornell has recorded more than 600 confirmed cases among students and staff in the last week alone, according to the university dashboard. While no infected students are seriously sick, Pollack said the university has "a role to play in reducing the spread."

-ABC News' Arielle Mitropoulos, Chris Donato

New York City Mayor Bill de Blasio warned that the city will have to brace for a jump in COVID-19 cases as the omicron variant continues to spread.

"We expect omicron to be a fast and temporary phenomenon. We expect these next weeks to see a very, very big surge in the number of cases, more than we've seen previously," he said during a news conference Sunday.

Roughly 162 patients were confirmed positive in the hospital, the mayor said. Hospitalizations have gone up, but not at the rate health officials were expecting.

"It will undoubtly grow a bit," de Blasio said.

The city recorded 5,731 new cases of COVID-19 Sunday.

The mayor urged New Yorkers to get vaccinated and to get their booster shots. The city's health department said as of Sunday 71% of all residents are fully vaccinated.

De Blasio also recommended that people wear masks indoors.

The city will focus on vaccination efforts for children and to increase booster access in nursing homes, he said.

At-home testing kits will be handed out at high volume testing sites, according to the mayor.