Last week, another 164,000 children in the United States tested positive for COVID-19, up by 24% from the week prior, according to a report released Monday by the American Academy of Pediatrics and the Children’s Hospital Association.

COVID-19 cases among U.S. children are "extremely high," the organizations wrote in the report.

Last week the Northeast saw its highest number of pediatric cases since the onset of the pandemic, with nearly 40,000 new cases.

So far, 21 million children ages 5 to 17 nationwide -- about 39.6% -- have received at least one dose of a COVID-19 vaccine.

Severe illness due to COVID-19 remains "uncommon" among children, the organizations wrote in the report. But they continue to warn that there is an urgent need to collect more data on the long-term consequences of the pandemic on kids, including the physical, emotional and mental health impacts.

-ABC News' Arielle Mitropoulos

A total of 50 million COVID-19 cases have now been confirmed in the U.S., according to data from Johns Hopkins University.

The U.S. has reported more cases than any other nation in the world. The U.S. currently represents nearly one-fifth of the globe's total 270.5 million cases.

-ABC News' Arielle Mitropoulos

In the weeks following Thanksgiving, the COVID-19 resurgence in the U.S. has escalated rapidly.

The U.S. is averaging more than 118,000 new cases each day -- up by about 41.8% in the last two weeks and up nearly 85% since late October, according to federal data.

Six states with some of the nation's highest vaccination rates are also among the states with the highest new case rates: New Hampshire, Vermont, Massachusetts, Maine, Rhode Island and New York. Experts say cases could be rising in the Northeast partially due to people heading inside in the cold weather.

Daily COVID-19-related hospital admissions increased by 14.4% in the last week and jumped by 48% in the last month, according to federal data.

Pediatric admissions are up by 23.8% in the last week.

-ABC News' Arielle Mitropoulos

Omicron is expected to be the dominant variant in London in the next 48 hours, the Secretary of State for Health and Social Care, Sajid Javid, warned in a statement to Parliament Monday.

Omicron represents 20% of England's cases and 44% of London's cases, Javid said.

"No variant of COVID-19 has spread this fast," Javid said.

Ten people with omicron are in U.K. hospitals.

"Hospitalisations and deaths lag infections by around two weeks," Javid said, "So we can expect those numbers to dramatically increase in the days and weeks that lie ahead."

"In preparation, the UK’s four Chief Medical Officers raised the COVID Alert level to 4, its second-highest level, this was done over the weekend. And NHS England has just announced it will return to its highest level of emergency preparedness: Level 4 National Incident," Javid said. "This means the NHS response to Omicron will be a coordinated as a national effort, rather than led by individual trusts."

Javid also urged people to get booster doses, stating that 40% of adults in the U.K. have gotten boosters so far.

-ABC News' Zoe Magee

School leaders at both New York University and Princeton University announced Wednesday that they will take steps to cancel end-of-year events and move winter exams online amid a surge in COVID-19 cases on their respective campuses.

"Given that we've seen an uptick in cases among undergraduates during the last 24 hours -- including suspected cases of the highly contagious Omicron variant -- we hope to avoid letting the final exam schedule interfere with students’ travel home for Winter Break," Princeton University's dean, Jill Dolan, and vice president for campus life, Rochelle Calhoun, said in a joint statement. "We certainly don’t want you remaining on campus in required isolation through the holidays."

All indoor gatherings with food and those where face coverings cannot be worn must be canceled or postponed at Princeton's New Jersey campus from Thursday through Jan. 7, according to the statement.

A statement from New York University's provost, Katherine Fleming, executive Vice President, Martin Dorph, and head of the COVID-19 prevention and response team, Dr. Carlo Ciotoli, said they "strongly encourage that final examinations and/or assessments be changed to remote/online format." All discretionary, non-essential, non-academic gatherings and events at the school's campus in New York City must be canceled "immediately," according to the statement.

"The continuous review of the data from our COVID-19 testing program has indicated a considerable acceleration in the rate of new cases in our community," they said. "It’s not a cause for alarm, but it is a cause for concern, caution, and appropriate actions."

NYU has also joined a growing list of colleges and universities across the nation that are requiring all eligible members of the school community, including faculty and students, to be fully vaccinated against COVID-19 and receive a booster shot ahead of the upcoming spring semester.

Meanwhile, officials at Cornell University in Ithaca, New York, announced Tuesday that they have moved the campus into a "level red" alert after identifying evidence of suspected cases of the omicron variant in a "significant" number of the school's COVID-19 positive samples from students.

According to data from the Centers for Disease Control and Prevention, the omicron variant is estimated to account for more than 13% of newly confirmed COVID-19 cases in the New York and New Jersey area -- the highest proportion of any region of the United States.

-ABC News' Chris Donato and Arielle Mitropoulos