COVID-19 updates: Elizabeth Warren tests positive

The senator says she's experiencing "mild symptoms."

As the COVID-19 pandemic has swept the globe, more than 5.3 million people have died from the disease worldwide, including over 806,000 Americans, according to real-time data compiled by Johns Hopkins University's Center for Systems Science and Engineering.

About 61.4% of the population in the United States is fully vaccinated against COVID-19, according to data from the Centers for Disease Control and Prevention.


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White House delays enforcement of workforce vaccine-or-test mandate

Enforcement of the Biden administration's vaccine-or-test mandate for private companies with more 100 employees will be delayed by a month, officials said.

The Labor Department’s Occupational Safety and Health Administration announced the change Saturday, a day after a federal appeals court lifted a stay on the rule, allowing it to proceed.

Previously, the mandate required companies to enforce masks among unvaccinated employees beginning Dec. 6, and either see proof of vaccination or begin testing workers weekly by Jan. 4.

The new deadlines for compliance are now Jan. 10 and Feb. 9, respectively, OSHA said.

-ABC News' Anne Flaherty


New York state sets another daily case record

Nearly 22,000 positive COVID-19 test results were reported in New York state in the last 24 hours, according to Gov. Kathy Hochul's office -- breaking a single-day record set the day before.

The 21,908 positive COVID-19 test results are out of 290,930 results reported -- for a 7.53% positivity rate.

Demand for testing also continues to rise, with about 27,000 more people getting tested on Friday.

"This is not like the beginning of the pandemic. We are prepared for the winter surge because we have the tools at our disposal," Hochul said in a statement. "Getting vaccinated, getting the booster and wearing a mask are critical to avoiding getting seriously ill from COVID-19, so don't take a chance."

-ABC News' Joshua Hoyos


President Biden to announce 'next steps' in COVID-19 response on Tuesday

President Joe Biden will deliver remarks this Tuesday on the country's fight against COVID-19 and "announce new steps" the administration will take amid the growing spread of the omicron variant, White House officials said.

The president will address steps the administration is taking "to help communities in need of assistance, while also issuing a stark warning of what the winter will look like for Americans that choose to remain unvaccinated," White House press secretary Jen Psaki said on Twitter Saturday afternoon.

The speech will come as millions of Americans prepare to travel and gather for the holidays, and as concerns about the omicron variant continue in the U.S. and around the world.

-ABC News' Molly Nagle


Over 10,000 additional confirmed omicron cases in UK

An additional 10,059 confirmed cases of the omicron variant of COVID-19 have been reported across the U.K., according to the U.K. Health Security Agency's daily omicron overview on Saturday.


Confirmed omicron cases in the U.K. now total 24,968.

-ABC News' Rashid Haddou


Pfizer says 'game changer' pills could save thousands of lives

Pfizer's forthcoming COVID-19 treatment could be authorized for emergency use in the United States by the end of this year or early next year, pending the Food and Drug Administration's regulatory timeline, Pfizer CEO Albert Bourla told ABC News.

The pharmaceutical giant announced Tuesday that it has submitted promising new data to the FDA, including lab experiments showing its oral antiviral medicine, Paxlovid, will likely work against the omicron variant. And in updated clinical trial data, Pfizer found the treatment reduces the risk of being hospitalized or dying by 89% when taken within three days of being diagnosed with COVID-19, and 88% when taken within five days of being diagnosed among high-risk, unvaccinated patients.

"It is a game changer," Bourla told ABC News. "But at the same time, I want to emphasize that no one should use the existence of the pill as an excuse to avoid vaccination."

Bourla said the medicine could save thousands of lives.

"We did some calculations how many deaths or hospitalizations can be avoided based on the current U.S. mortality rates and the current U.S. hospitalization rates," he said. "On the back-of-the-envelope calculation, we estimate that 100,000 people if they take the pill, we will avoid 6,000 hospitalizations and 1,200 deaths approximately."

-ABC News' Sony Salzman