The new COVID-19 variant first identified in the United Kingdom could increase the trajectory of the virus in the United States, according to a report released by the Centers for Disease Control and Prevention on Friday.

Unless new mitigation measures are taken, the variant, known as B.1.1.7, is likely to become the predominant variant in the U.S. by March, the report warned. The CDC called for "universal compliance" with public health measures and more genomic surveillance to monitor new variants and mutations.

"Higher vaccination coverage might need to be achieved to protect the public," according to the report. While the new variant is not more deadly than the old one, it is thought to be more transmissible, meaning that it could lead to more cases, and ultimately more hospitalizations and deaths.

-ABC News' Sony Salzman contributed to this report.

Deaths from COVID-19 reached a grim new milestone Friday, with 2,00,905 fatalities reported around the world since the pandemic began, according to data from Johns Hopkins University.

The United States leads the world in COVID-19 deaths, with 389,581 fatalities, followed by Brazil, India, Mexico and the United Kingdom.

-ABC News' Rachel Katz contributed to this report.

Dr. Anthony Fauci called President-elect Joe Biden's promise to administer 100 million COVID-19 shots in the first 100 days of his term "quite feasible" during an interview with NBC's "Today" show Friday. He said he hopes the United States can get to 70% or 80% vaccination within several months.

Part of the distribution holdup, according to Fauci, has been careful prioritization by states. "If you have a dose, give it," he urged states. "Don't be so rigid as to those early designations."

Reaching those goals, however, depends on vaccine uptake. "When a vaccine becomes available, get vaccinated,” Fauci pleaded with the public.

-ABC News' Anne Flaherty contributed to this report.

U.S. President-elect Joe Biden has chosen Dr. David Kessler, former commissioner of the Food and Drug Administration (FDA), to help lead the federal government's COVID-19 vaccine initiative.

Kessler, a pediatrician and lawyer who headed the FDA from 1999 to 1997 under the Bush and Clinton administrations, will replace Dr. Moncef Slaoui, who is the current chief science officer to Operation Warp Speed.

Biden also announced several other appointees who will join his incoming administration's COVID-19 response team.

"We are in a race against time, and we need a comprehensive strategy to quickly contain this virus," Biden said in a statement Thursday. "The individuals announced today will bolster the White House’s COVID-19 Response team and play important roles in carrying out our rescue plan and vaccination program. At a time when American families are facing numerous challenges I know these public servants will do all that is needed to build our nation back better."

Weeks after video emerged of mostly maskless partygoers at U.S. President Donald Trump's Mar-a-Lago Club in Palm Beach, county officials are cracking down.

Palm Beach County sent a letter this week, acquired by ABC News, warning the club and saying officials had met with representatives from the club about violations. Masks are mandatory in the county in all businesses or establishments, and anywhere in public social distancing cannot be maintained. The mandate is currently in place through Jan. 20 -- the same day the county's most famous resident will be exiting the White House.

"Thank you for meeting with us last week to discuss the concerning allegations regarding the Mar a Lago New Year's Eve party and lack of facial coverings being worn during evening activities," the county wrote in the letter addressed to Bernd Lembcke, executive vice president and managing director of Mar-a-Lago Club.

"We recount that you provided masks for all party goers who attended the party and that you provided additional masks for those that walked from the reception area to the main dining ballroom," the letter continued. "Although you provided these important steps, it seemed that based on the video evidence, there was a breakdown in enforcement of the mask orders that led to almost the entire room of guests being without masks during the later evening activities."

The letter also includes a confirmation of the violation, which is a first-time warning, that lays out a fine of up to $15,000 for each potential future violation.

Trump has consistently downplayed wearing masks over the course of the entire pandemic. Despite telling people to wear masks on occasion at official briefings, he also mocked others for wearing them, including President-elect Joe Biden. Many supporters have decried mandates and openly flouted rules, including maskless Trump supporters who stormed the Capitol last week.

ABC News' Will Gretsky contributed to this report.