New COVID-19 cases in the U.S. are seeing a "very encouraging" drop, according to The COVID Tracking Project.

The number of weekly cases decreased 21% as of Saturday, the tracker said. There were "more modest but very welcome" drops in COVID-19 deaths and hospitalizations as well.

The seven-day average for cases is back to "pre-Thanksgiving levels," though the group noted there are still nearly three times as many new cases daily compared to the summer peak.

Los Angeles County has crossed 15,000 deaths, with about one-third of those deaths happening in 2021.

Health officials reported 269 deaths in the county on Saturday. LA remains the hardest-hit county in the United States. LA County has more than twice as many cases (1,064,887) as the second-highest in the nation (Arizona's Maricopa County; 444,431, according to Johns Hopkins University).

The county said 5,106 people have died since Dec. 30.

There was a little bit of good news in LA, however, as the county is following national trends of dropping hospitalizations. The number of people in hospitals with COVID-19 dropped under 7,000 for the first time since Dec. 29, according to the health department.

"Many people continue to spread this virus and, tragically, now more than 15,000 people have died from COVID-19 in Los Angeles County," Dr. Barbara Ferrer, the county's director of public health, said in a statement. "While we are seeing some positive data in daily new cases and hospitalizations, we are far from out of the woods. It is critically important we slow COVID-19 spread to decompress the strain on our healthcare system and save lives."

ABC News' Matthew Fuhrman contributed to this report.

Week-to-week comparisons show new deaths and new cases are on the decline nationwide, according to an internal Department of Health and Human Services memo obtained by ABC News.

Thirty-one states and territories are in a downward trajectory of new cases, according to the memo. Twenty states and territories are in an upward trajectory of new cases while five jurisdictions are at a plateau.

The U.S. saw 1,318,915 new cases from Jan. 16 to Jan. 22 -- a 20.3% decrease from the previous week.

There were 21,442 deaths reported from Jan. 16 to Jan. 22, which was a 7.7% decrease from the week before.

The national test-positivity rate also dropped, falling from 11.9% to 10.4% in week-to-week comparisons, the memo said.

ABC News’ Josh Margolin contributed to this report.

Indoor dining resumed in Chicago on Saturday as the city moved to “Tier 1” of reopening “due to recent progress in the fight against COVID-19,” Mayor Lori Lightfoot said.

Indoor dining is limited to 25 people or 25% capacity with tables six feet apart.

All bars and restaurants must close at 11 p.m.

"We have long pushed for the careful resumption of limited indoor dining, and I am thrilled that we have made enough progress … to reopen our businesses and bring workers back," Lightfoot said in a statement, according to ABC Chicago station WLS.

Wednesday marks one year since the Centers for Disease Control and Prevention confirmed the first case of COVID-19 in the United States.

It wouldn't be until several months later that scientists identified the virus that caused COVID-19 in blood samples from people in various U.S. states as early as December 2019.

Since the first confirmed case 365 days ago, more than 24.2 million people in the U.S. have tested positive for COVID-19, which means that approximately one in every 13 Americans have contracted the disease, according to data collected by Johns Hopkins University.

At least 402,400 lives in the U.S. have been lost to COVID-19, representing approximately 19.5% of the worldwide death toll from the disease. That means one in every 823 Americans have now died from COVID-19.

New York remains the worst-hit U.S. state in terms of COVID-19 deaths -- with more than 37,000 confirmed fatalities -- followed by Texas, California and Florida.

Since the start of the pandemic, nearly 763,000 people in the U.S. have been hospitalized with COVID-19. Just under 124,000 people nationwide are currently hospitalized with the disease. In the last two weeks, that number has declined by 5.6%, according to data compiled by The COVID Tracking Project, a volunteer-run effort to track the U.S. outbreak.

January has already proven to be one of the worst months on record for the U.S. outbreak. In the first 19 days of 2021, the country has confirmed more than 4.15 million cases and over 55,000 deaths from the disease.

Although the numbers are currently impacted by the holiday weekend, the U.S. continues to see a drop in new infections, now averaging approximately 197,000 newly confirmed cases per day, according to The COVID Tracking Project.

ABC News' Brian Hartman and Arielle Mitropoulos contributed to this report.