An adult in South Carolina’s Lowcountry region has become the state’s first confirmed case of the United Kingdom COVID-19 variant, South Carolina’s Department of Health and Environmental Control said.

The person "has an international travel history," the department said.

The U.S. has confirmed at least 434 cases of the B.1.1.7 U.K. variant across 30 states, South Carolina officials said.

"Experts agree that existing vaccines work to protect us from this variant, even if we don’t know just how effective they are," the South Carolina officials said. "At this time, there’s no conclusive evidence to prove that the B.1.1.7 variant causes more severe illness."

ABC News’ Josh Hoyos contributed to this report.

The Coachella Valley Music and Arts and Stagecoach Country Music festivals, set for April, were canceled on Friday by Dr. Cameron Kaiser, health officer for Riverside County, California.

Riverside County’s positivity rate stands at 20%. The county has 0% bed availability in its intensive care units.

January has been the deadliest month since the pandemic began, with 90,844 total deaths, according to data compiled by Johns Hopkins University.

The U.S. coronavirus death toll stands at 436,810 -- with the Center for Disease Control and Prevention projecting that more than 77,000 deaths could be reported by Feb. 20.

California is now the second U.S. state with known detection of the Brazil P.1 variant.

Minnesota health officials confirmed earlier this week the nation's first known COVID-19 case associated with the variant.

Inside Stanford's Clinical Virology Laboratory, Dr. Benjamin Pinsky and his team found two strains of the virus: the Brazil strain and the U.K. strain, KGO reported Saturday morning.

"It's in about 17% of the samples that we've sequenced," Pinsky told KGO.

There were 152,478 new cases of COVID-19 confirmed in the United States on Wednesday, according to a real-time count kept by Johns Hopkins University.

Wednesday's case count is far less than the country's all-time high of 300,282 newly confirmed infections on Jan. 2, Johns Hopkins data shows.

An additional 3,943 fatalities from COVID-19 were registered nationwide on Wednesday, down from a peak of 4,466 new deaths on Jan. 12, according to Johns Hopkins data.

COVID-19 data may be skewed due to possible lags in reporting over the Martin Luther King Jr. Day holiday weekend.

A total of 25,598,062 people in the U.S. have been diagnosed with COVID-19 since the pandemic began, and at least 429,195 have died, according to Johns Hopkins data. The cases include people from all 50 U.S. states, Washington, D.C., and other U.S. territories as well as repatriated citizens.

Much of the country was under lockdown by the end of March as the first wave of pandemic hit. By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country's cases then hovered around 20,000 for a couple of weeks before shooting back up over the summer.

The numbers lingered around 40,000 to 50,000 from mid-August through early October before surging again to record levels, crossing 100,000 for the first time on Nov. 4, then reaching 200,000 on Nov. 27 before topping 300,000 on Jan. 2.

So far, the U.S. Food and Drug Administration has authorized two COVID-19 vaccines for emergency use -- one developed by U.S. pharmaceutical giant Pfizer and its German partner BioNTech, and another developed by American biotechnology company Moderna and the National Institute of Allergy and Infectious Diseases. More than 24 million vaccine doses have been administered nationwide, according to the latest data from the Centers for Disease Control and Prevention.