The new COVID-19 variant first identified in the United Kingdom could increase the trajectory of the virus in the United States, according to a report released by the Centers for Disease Control and Prevention on Friday.

Unless new mitigation measures are taken, the variant, known as B.1.1.7, is likely to become the predominant variant in the U.S. by March, the report warned. The CDC called for "universal compliance" with public health measures and more genomic surveillance to monitor new variants and mutations.

"Higher vaccination coverage might need to be achieved to protect the public," according to the report. While the new variant is not more deadly than the old one, it is thought to be more transmissible, meaning that it could lead to more cases, and ultimately more hospitalizations and deaths.

-ABC News' Sony Salzman contributed to this report.

Deaths from COVID-19 reached a grim new milestone Friday, with 2,00,905 fatalities reported around the world since the pandemic began, according to data from Johns Hopkins University.

The United States leads the world in COVID-19 deaths, with 389,581 fatalities, followed by Brazil, India, Mexico and the United Kingdom.

-ABC News' Rachel Katz contributed to this report.

Dr. Anthony Fauci called President-elect Joe Biden's promise to administer 100 million COVID-19 shots in the first 100 days of his term "quite feasible" during an interview with NBC's "Today" show Friday. He said he hopes the United States can get to 70% or 80% vaccination within several months.

Part of the distribution holdup, according to Fauci, has been careful prioritization by states. "If you have a dose, give it," he urged states. "Don't be so rigid as to those early designations."

Reaching those goals, however, depends on vaccine uptake. "When a vaccine becomes available, get vaccinated,” Fauci pleaded with the public.

-ABC News' Anne Flaherty contributed to this report.

U.S. President-elect Joe Biden has chosen Dr. David Kessler, former commissioner of the Food and Drug Administration (FDA), to help lead the federal government's COVID-19 vaccine initiative.

Kessler, a pediatrician and lawyer who headed the FDA from 1999 to 1997 under the Bush and Clinton administrations, will replace Dr. Moncef Slaoui, who is the current chief science officer to Operation Warp Speed.

Biden also announced several other appointees who will join his incoming administration's COVID-19 response team.

"We are in a race against time, and we need a comprehensive strategy to quickly contain this virus," Biden said in a statement Thursday. "The individuals announced today will bolster the White House’s COVID-19 Response team and play important roles in carrying out our rescue plan and vaccination program. At a time when American families are facing numerous challenges I know these public servants will do all that is needed to build our nation back better."

There were 229,610 new cases of COVID-19 confirmed in the United States on Wednesday, according to a real-time count kept by Johns Hopkins University.

It's the ninth straight day that the country has reported more than 200,000 new cases. Wednesday's tally is less than the country's all-time high of 302,506 newly confirmed infections on Jan. 2, Johns Hopkins data shows.

An additional 3,959 new deaths from COVID-19 were registered nationwide on Wednesday, down from a peak of 4,327 fatalities logged the previous day, according to Johns Hopkins data.

COVID-19 data may be skewed due to possible lags in reporting over the holidays followed by a potentially very large backlog.

A total of 23,079,163 people in the U.S. have been diagnosed with COVID-19 since the pandemic began, and at least 384,794 have died, according to Johns Hopkins data. The cases include people from all 50 U.S. states, Washington, D.C., and other U.S. territories as well as repatriated citizens.

Much of the country was under lockdown by the end of March as the first wave of pandemic hit. By May 20, all U.S. states had begun lifting stay-at-home orders and other restrictions put in place to curb the spread of the novel coronavirus. The day-to-day increase in the country's cases then hovered around 20,000 for a couple of weeks before shooting back up over the summer.

The numbers lingered around 40,000 to 50,000 from mid-August through early October before surging again to record levels, crossing 100,000 for the first time on Nov. 4, then reaching 200,000 on Nov. 27 before topping 300,000 on Jan. 2.