South African President Cyril Ramaphosa is receiving treatment for "mild COVID-19 symptoms" after testing positive for the virus on Sunday, his office said in a statement.

Ramaphosa, 69, began feeling unwell earlier Sunday after leaving a state memorial service in Cape Town in honor of Frederik Willem de Klerk, South Africa's last apartheid president and a Nobel laureate, who died last month. Ramaphosa, who is fully vaccinated against COVID-19, was experiencing "mild" symptoms and a test confirmed he was infected, according to his office. The statement didn't say whether he has the omicron variant, which was discovered by scientists in southern Africa last month and is spreading rapidly.

Ramaphosa is self-isolating in Cape Town and is being monitored by the South African Military Health Service. He has delegated all his responsibilities to Deputy President David Mabuza for the next week, his office said.

Last week, Ramaphosa traveled with a delegation to four West African nations. He and the members of the South African delegation were all tested for COVID-19 in each of the countries during their trip. They returned to South Africa on Dec. 8, after testing negative in Senegal. Ramaphosa tested negative again upon arriving in Johannesburg that day, according to his office.

The statement advised people who had contact with the South African president on Sunday to watch for symptoms or to get tested for COVID-19.

"President Ramaphosa says his own infection serves as a caution to all people in the country to be vaccinated and remain vigilant against exposure," his office said in the statement. "Vaccination remains the best protection against severe illness and hospitalization."

-ABC News' Christine Theodorou

White House COVID-19 response coordinator Jeff Zients warned Friday that the unvaccinated are "looking at a winter of severe illness and death -- for yourselves, your families and the hospitals you may soon overwhelm."

CDC director Rochelle Walensky said she expects omicron to become the dominant variant in the coming weeks.

Asked whether the CDC will change its guidance on vaccinated people quarantining after exposure, which they currently don't have to, Walensky said, "We are actively following the science in that area, with regard to how the viral burden is both among vaccinated people and unvaccinated people, and the natural history of that viral burden with regard to isolation."

"And as that science emerges, we will update our evidence if need be," she said.

-ABC News' Cheyenne Haslett