A group of New York City public school teachers asked the U.S. Supreme Court Thursday to block the city’s vaccine mandate for school employees, claiming it violates their due process and equal protection rights.

The unvaccinated teachers said they should be given an option to regularly test rather than forced to get the shot and they accused the city of failing to explain why that alternative was not made available.

“If permitted to take effect, the August 23 Order will force thousands of unvaccinated public-school employees to lose their jobs -- while other municipal employees, including those who have significant contact with children, are allowed to opt-out of the vaccine mandate through weekly COVID-19 testing,” the petition said.

“While a temporary interruption of work is not actionable, the mandate here would have a permanent effect: it is open-ended, where if a teacher never gets vaccinated, he or she will never be able to return to work,” the petition said.

A federal appeals court earlier this week dissolved a temporary injunction and allowed the mandate to stand. The city has given school employees until Friday afternoon to comply before enforcement begins Monday.

-ABC News' Aaron Katersky

Out of the African continent's 1.3 billion population, 60 million people have now been fully vaccinated against COVID-19, the World Health Organization said Tuesday.

Fifteen African countries met the WHO's goal to fully vaccinate at least 10% of residents by Sept. 30. (Nearly 90% of high-income countries have met this target.)

Twenty-three million vaccines arrived in Africa in September, 10 times the number delivered in June. COVAX is working to identify countries that can absorb large volumes of vaccines.

COVID-19 cases in Africa are on the decline. There were 74,000 new cases reported the week of Sept. 16, a 35% drop from the previous week.

-ABC News' Christine Theodorou

After announcing 593 employees would be fired for not complying with United's vaccine mandate, the airline says just 320 employees will be terminated.

“Our vaccine policy continues to prove requirements work - in less than 48 hours, the number of unvaccinated employees who began the process of being separated from the company has been cut almost in half, dropping from 593 to 320," United said.
 
-ABC News' Sam Sweeney

Northwell Health, New York state's largest health care system, says its workforce of more than 77,000 is now “near 100%” vaccinated after letting go “a few hundred employees” who refused to get the mandated shot.

Northwell Health said, "we are pleased to report that most team members are opting to be vaccinated so as to avoid being terminated."