COVID-19 updates: Pfizer vaccine highly effective in children 5-11
About 64.3 million Americans ages 12 and older are completely unvaccinated.
More than 731,000 Americans have died from COVID-19 while over 4.9 million people have died from the disease worldwide, according to real-time data compiled by the Center for Systems Science and Engineering at Johns Hopkins University.
Just 66.9% of Americans ages 12 and up are fully vaccinated against COVID-19, according to data from the Centers for Disease Control and Prevention.
Latest headlines:
FDA could authorize Moderna, J&J booster shots Wednesday
The FDA could authorize Moderna and Johnson & Johnson booster shots for some populations as soon as Wednesday.
Meanwhile, the CDC independent advisory committee is meeting Wednesday to discuss vaccines in general. The committee is expected to debate Moderna and Johnson & Johnson on Thursday, discussing who boosters should be recommended for and if mixing and matching vaccines should be permitted.
A non-binding vote is expected at the end of Thursday.
The CDC director is expected to make the final recommendations shortly after the vote, which could come as soon as Thursday night or Friday morning.
-ABC News' Eric M. Strauss
NYC to mandate vaccine for municipal workers
New York City Mayor Bill de Blasio on Wednesday announced a COVID-19 vaccine mandate for all municipal workers.
The mandate is expected to include all employees from sanitation workers to office workers and will require some 161,000 workers to have their first dose by Oct. 29.
Municipal employees who do not get vaccinated will be placed on unpaid leave, and their future employment will be resolved in negotiations with individual labor unions.
Correction officers will face a later deadline of Dec. 1.
-ABC News' Aaron Katersky
Secretary Mayorkas tests positive for COVID-19
Department of Homeland Security Secretary Alejandro Mayorkas has tested positive for COVID-19, a DHS spokeswoman confirmed to ABC News.
Mayorkas, who is fully vaccinated, "is experiencing only mild congestion," a statement said.
Mayorkas will work from home, the statement said. Contact tracing is underway.
There were no major White House officials deemed to be close contacts. "No White House principal has been determined to be a close contact of Secretary Mayorkas, given that the most recent contact was at the outdoor National Peace Officers’ Memorial Service, which took place outside of the 48-hour close contact window,” the White House said in a statement.
-ABC News' Luke Barr
Pfizer vaccine 93% effective against hospitalizations for 12-18 age group
A new CDC study found that the Pfizer vaccine was 93% effective against hospitalizations for adolescents ages 12 to 18 from July to September.
The researchers also found that nearly all (97%) of adolescents ages 12 to 18 who were hospitalized with COVID-19 were unvaccinated.
-ABC News' Sony Salzman
US deaths estimated to continue to fall in weeks ahead, though thousands more lost
Forecast models used by the CDC are predicting that weekly COVID-19 death totals in the U.S. will likely continue to drop in the weeks to come, though thousands of Americans are still expected to lose their lives to the virus.
The model expects approximately 18,000 deaths to occur in the next two weeks, with a total of around 757,000 deaths recorded in the U.S. by Nov. 13.
The ensemble model estimates that 19 states and territories of the U.S. have a greater than 50% chance of having more deaths in the next two weeks compared to the past two weeks, and that four states and territories (Alaska, Nebraska, Ohio and American Samoa) have a greater than 75% chance of an increase over the next two weeks.
-ABC News' Arielle Mitropoulos