Hezbollah claimed the launch of a Qadir-1 ballistic missile targeting the Mossad intelligence agency's headquarters on the outskirts of Tel Aviv on Wednesday morning.

"It is the headquarters responsible for the assassination of leaders and the bombing of pagers and hand-held radios," the militant group said in a statement, referring to last week's communication device explosions in Lebanon and Syria.

Sirens sounded in Tel Aviv amid the attack. "One surface-to-surface missile was identified crossing from Lebanon and was intercepted," the Israel Defense Forces said in a statement.

The IDF later said in a social media post that it destroyed the launcher from which the missile was fired in southern Lebanon.

The launch at Tel Aviv is the first time Hezbollah has attacked the city in central Israel since the war in the Gaza Strip began on Oct. 7.

-ABC News' Jordana Miller, Ghazi Balkiz, Jason Volack and Joe Simonetti

Hezbollah has confirmed the death of rocket and missile division commander Ibrahim Qubaisi in a post on their Telegram channel.

Hezbollah said he was killed in southern Lebanon.

Earlier Tuesday, the Israel Defense Forces said an Israeli air attack in Da'ahia in Beirut killed Qubaisi.

-ABC News' Ellie Kaufman

Israeli forces targeted eight residential homes in the Gaza Strip over the past 24 hours, killing at least 52 people, spokesperson Major Mahmoud Basal of the Hamas-run Gaza Civil Defense said Tuesday.

At least five of those people were killed after a house in the town of Al-Nasr, northeast of Rafah, was targeted, the civil defense spokesperson added.

The IDF said they were conducting "precise, intelligence-based operations in the Rafah area" in a statement Tuesday.

-ABC News' Sami Zyara and Jordana Miller

The number of people displaced in southern Lebanon as a result of Israeli airstrikes may be approaching half a million, according to Lebanese Foreign Minister Bou Habib, who stressed that "the war in Lebanon will not help the Israelis return to their homes, and negotiations are the only way to do so."

Habib spoke at an event hosted by the Carnegie Endowment for International Peace on Tuesday while attending the United Nations General Assembly.

He expressed his "disappointment" over U.S. President Joe Biden’s speech at the U.N., saying it was "neither strong nor promising and will not solve this problem," but said he "hopes that Washington can intervene to help."

"Lebanon cannot end the fighting alone and needs America's help, despite past disappointments," Habib said, adding that the U.S. is "the only country that can truly make a difference in the Middle East and with regard to Lebanon."

-ABC News' William Gretsky