Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes
The IDF says it struck military targets of terrorist organizations in Gaza.
Israel launched a retaliatory strike against Iran early Friday morning local time, a senior U.S. official told ABC News.
The strike followed Iran's attack on Saturday, when Tehran sent a volley of more than 300 drones and missiles toward targets in Israel, according to Israeli military officials. All but a few were intercepted by Israel and its allies, including the United States, officials said.
Iran's weekend attack came more than six months after Hamas terrorists invaded Israel on Oct. 7, after which the Israeli military began its bombardment of Gaza.
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What to know about Iran's attack on Israel
Israeli officials said the country's Iron Dome defense system endured a big test from Iran's attack on Saturday, intercepting 99% of the 300 "threats of various types" thrown at it.
Iran's Islamic Revolutionary Guard Corps, according to Israel Defense Forces spokesperson Daniel Hagari, launched 170 unmanned aerial vehicles (UAVs), more than 120 ballistic missiles and more than 30 cruise missiles in the attack.
Hagari said "99% of the threats launched towards Israeli territory were intercepted -- a very significant strategic achievement."
Hagari said the attack resulted in only one known Israeli casualty, a 7-year-old girl who was severely injured when she was struck by shrapnel apparently from an intercepted missile.
No damage to Iran’s nuclear sites after Israeli strike: IAEA
Iran's nuclear sites have not been damaged by Israel's strike on Iran early Friday morning, according to the International Atomic Energy Agency (IAEA).
In a statement released on social media, IAEA chief Rafael Grossi says he "continues to call for extreme restraint from everybody and reiterates that nuclear facilities should never be a target in military conflicts."
Flight operations resume in Iran: State media
After suspending flights at several airports following reports of an explosion in Iran, Iranian state media said early Friday normal operations have resumed.
-ABC News' Will Gretsky
Flights to Tehran, Isfahan and Shiraz suspended after reports of explosion in Iran: Iranian state media
Flights to Tehran, Isfahan and Shiraz have been suspended following reports an explosion was heard in the city of Qahjavaristan, Iranian state media reported.
The city of Qahjavaristan is located near Isfahan Airport and the 8th Shekhari Base of the Army Air Force in the northwest of Isfahan.
-ABC News' Will Gretsky
Israeli missiles have hit a site in Iran
A U.S. official confirmed to ABC News Israeli missiles have hit a site in Iran. The official could not confirm whether Syria and Iraq sites were hit as well.
-ABC News' Martha Raddatz
Biden calls for cease-fire 'now' to get aid into Gaza in Univision interview
President Joe Biden called for an immediate cease-fire to get food and aid into Gaza in an interview airing Tuesday night on Univision.
"So I what I'm calling for is for the Israelis to just call for a cease-fire, allow for the next six, eight weeks total access to all food and medicine going into the country," Biden said in the interview with Univision's Enrique Acevedo. "I've spoken with everyone from the Saudis to the Jordanians to the Egyptians. They're prepared to move in. They're prepared to move this food in. And I think there's no excuse to not provide for the medical and the food needs of those people. It should be done now."
Biden did not mention tying the cease-fire to a hostage deal, according to a transcript of the interview, which would be a shift for the administration. ABC News has reached out to the White House for comment.
Last week, officials pushed back on suggestions that they were separating calls for a cease-fire from hostage negotiations in their readout of Biden's call with Israeli Prime Minister Benjamin Netanyahu.
"Our conviction remains that we need to see an immediate cease-fire to enable the release of hostages but also to enable a dramatic surge in humanitarian assistance, as well as obviously better protecting civilians," Secretary of State Antony Blinken said on April 4.
In the Univision interview, Biden also called Netanyahu's approach in Gaza "a mistake" when asked if he believed the prime minister was "more concerned about his political survival than he is in the national interest of his people" as calls for Netanyahu's resignation have increased following the strike that killed seven World Central Kitchen workers.
"Well, I will tell you, I think what he's doing is a mistake. I don't agree with his approach. I think it's outrageous that those four, three vehicles were hit by drones and taken out on a highway where it wasn't like it was along the shore, it wasn't like there was a convoy moving there, etc.," Biden said in the interview.
The hour-long interview, which is airing at 10 p.m. ET, was taped a day before Biden's call with Netanyahu on April 4.
-ABC News' Molly Nagle