Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes
The IDF says it struck military targets of terrorist organizations in Gaza.
Israel launched a retaliatory strike against Iran early Friday morning local time, a senior U.S. official told ABC News.
The strike followed Iran's attack on Saturday, when Tehran sent a volley of more than 300 drones and missiles toward targets in Israel, according to Israeli military officials. All but a few were intercepted by Israel and its allies, including the United States, officials said.
Iran's weekend attack came more than six months after Hamas terrorists invaded Israel on Oct. 7, after which the Israeli military began its bombardment of Gaza.
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What to know about Iran's attack on Israel
Israeli officials said the country's Iron Dome defense system endured a big test from Iran's attack on Saturday, intercepting 99% of the 300 "threats of various types" thrown at it.
Iran's Islamic Revolutionary Guard Corps, according to Israel Defense Forces spokesperson Daniel Hagari, launched 170 unmanned aerial vehicles (UAVs), more than 120 ballistic missiles and more than 30 cruise missiles in the attack.
Hagari said "99% of the threats launched towards Israeli territory were intercepted -- a very significant strategic achievement."
Hagari said the attack resulted in only one known Israeli casualty, a 7-year-old girl who was severely injured when she was struck by shrapnel apparently from an intercepted missile.
Blinken condemns attack
Secretary of State Antony Blinken condemned Iran's attack on Israel, saying the U.S. doesn't seek escalation but will support Israel's right to defend itself and will protect U.S. personnel in the Middle East.
"The United States condemns Iran's attack on Israel in the strongest terms," Blinken said in a statement.
He added that he'll be "consulting with allies and partners in the region and around the world in the hours and days ahead."
-ABC News' Shannon K. Crawford
US shot down about 70 Iranian drones in Israel, officials say
Two U.S. officials confirmed that U.S. forces shot down about 70 Iranian drones headed towards Israel.
One official added that one of the U.S. Navy destroyers in the eastern Mediterranean was also able to bring down an undetermined number of Iranian ballistic missiles.
One of the officials said the destroyer shot down three Iranian ballistic missiles.
-ABC News’ Luis Martinez
Shelter in place lifted in some areas of Israel
The Israel Defense Forces Aerial Defense Array successfully intercepted the majority of Iran's surface-to-surface missile launches using the "Arrow" Aerial Defense System, together with Israel's strategic allies, before the launches crossed into Israeli territory.
A small number of hits were identified, including at an IDF base in southern Israel, where minor damage was caused to infrastructure.
Over the past few hours, many dozens of hostile aircraft, as well as dozens of cruise missiles, from Iran were identified approaching Israeli territory and intercepted. Dozens of IAF fighter jets are currently operating to intercept all aerial threats approaching Israeli territory.
According to a situation analysis by IDF’s Home Front Command, the residents of the following towns: Northern Golan, Nevatim, Dimona, Eilat-City, Be'er Sheva and Arad no longer need to stay near a protected space.
The IDF said it is deployed on all fronts, prepared, and continuing to defend Israeli territory.
-ABC News' Will Gretsky
US helped 'take down nearly all' incoming drones, missiles: Biden
The U.S. helped "Israel take down nearly all of the incoming drones and missiles," President Joe Biden said in a statement late Saturday evening.
The president also detailed his call with Israeli Prime Minister Benjamin Netanyahu following the attacks, where Biden said he reaffirmed America's "ironclad commitment to the security of Israel." He also said that his team would stay in "close touch" with Israel's leaders.
Biden said his team will engage with the G7 leaders on Sunday to coordinate a "united diplomatic response to Iran’s brazen attack."
He noted that though American forces were not impacted, forces will continue to monitor and "will not hesitate to take all necessary action to protect our people."
-ABC News' Michelle Stoddart
Iranian president warns of 'heavier' response if Israel strikes again
Iranian President Ebrahim Raisi claimed Sunday that Iran had taught Israel a lesson and warned of a "heavier" response to "any new adventures against the interests of the Iranian nation."
Iran said Israel was targeted in retaliation for its strike earlier this month on the Iranian Consulate in Damascus, Syria, that killed a top Iranian military leader.
"Following the instructions of Imam Khamenei, the Supreme Leader of the Islamic Revolution, and with the support of the proud nation and the powerful armed forces of Islamic Iran, I emphasize that any new adventure against the interests of the Iranian nation will be responded with a heavier and regrettable response from the Islamic Republic of Iran," Raisi said.
-ABC News' Edward Szekeres