Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes

The IDF says it struck military targets of terrorist organizations in Gaza.

Israel launched a retaliatory strike against Iran early Friday morning local time, a senior U.S. official told ABC News.

The strike followed Iran's attack on Saturday, when Tehran sent a volley of more than 300 drones and missiles toward targets in Israel, according to Israeli military officials. All but a few were intercepted by Israel and its allies, including the United States, officials said.

Iran's weekend attack came more than six months after Hamas terrorists invaded Israel on Oct. 7, after which the Israeli military began its bombardment of Gaza.


What to know about Iran's attack on Israel

Israeli officials said the country's Iron Dome defense system endured a big test from Iran's attack on Saturday, intercepting 99% of the 300 "threats of various types" thrown at it.

Iran's Islamic Revolutionary Guard Corps, according to Israel Defense Forces spokesperson Daniel Hagari, launched 170 unmanned aerial vehicles (UAVs), more than 120 ballistic missiles and more than 30 cruise missiles in the attack.

Hagari said "99% of the threats launched towards Israeli territory were intercepted -- a very significant strategic achievement."

Hagari said the attack resulted in only one known Israeli casualty, a 7-year-old girl who was severely injured when she was struck by shrapnel apparently from an intercepted missile.


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UK prime minister 'gravely concerned' about humanitarian situation in Gaza

U.K. Prime Minister Rishi Sunak spoke on the phone with Israeli Prime Minister Benjamin Netanyahu on Tuesday. While Netanyahu thanked Sunak for the U.K.'s support to counter Iran's weekend attack on Israel, Sunak also had harsh words for Netanyahu about the deepening humanitarian crisis in Gaza.

"On Gaza, the Prime Minister said he remained gravely concerned about the deepening humanitarian crisis," a Downing Street spokesperson said. "The U.K. wanted to see a massive step change in aid access to flood Gaza with vital supplies, including Israel opening up new aid routes as quickly as possible. The Prime Minister said it was deeply disappointing that Hamas blocked a deal at the weekend that would have saved Palestinian lives and secured the safe release of hostages."


Israeli war cabinet meeting ends again with no final decision on response: Source

Prime Minister Benjamin Netanyahu's war cabinet met for the third day in a row on Tuesday to consider an Israeli response to Iran's weekend attack.

But Tuesday’s meeting ended with no final decision made about an Israeli response, according to an Israeli source with knowledge of the meeting. A variety of options are still being considered, the source said.


Iran foreign minister says 'no intention of further escalating the situation'

Iranian Foreign Minister Hossein Amir-Abdollahian told Chinese Foreign Minister Wang Yi on a call that "Iran is willing to exercise restraint and has no intention of further escalating the situation," according to the Chinese foreign ministry’s readout of the conversation.


More than 19,000 children orphaned in Gaza

Over 10,000 women have been killed in Gaza during the war, according to a report from UN Women, the United Nations’ entity for gender equality and women's empowerment.

Out of those 10,000 women, 6,000 were mothers, who have left behind 19,000 orphaned children, according to the report.

-ABC News’ Kori Skillman


Israel makes significant process in preparations for Rafah evacuations: Source

Israel has made significant progress in preparations for the evacuation of around 1 million civilians from Rafah ahead of the Israeli military’s impending operation in the southern Gaza city, according to an Israeli source.

Preparations have been ongoing for over a month, including repairing water and sewage pipes and amassing thousands of tents, the source said.

There are around 1.5 million Palestinians estimated to be in the Khan Younis and Rafah areas in southern Gaza. It’s believed around 1 million people would evacuate north. The evacuation process, which could take weeks, would not start until after Passover.

State Department principal deputy spokesperson Vedant Patel stressed to reporters that "any kind of forced relocation or displacement of the Palestinian people within Gaza cannot and should not be part of any plan or an operation."

-ABC News’ Matt Gutman and Anne Flaherty