Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes
The IDF says it struck military targets of terrorist organizations in Gaza.
Israel launched a retaliatory strike against Iran early Friday morning local time, a senior U.S. official told ABC News.
The strike followed Iran's attack on Saturday, when Tehran sent a volley of more than 300 drones and missiles toward targets in Israel, according to Israeli military officials. All but a few were intercepted by Israel and its allies, including the United States, officials said.
Iran's weekend attack came more than six months after Hamas terrorists invaded Israel on Oct. 7, after which the Israeli military began its bombardment of Gaza.
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What to know about Iran's attack on Israel
Israeli officials said the country's Iron Dome defense system endured a big test from Iran's attack on Saturday, intercepting 99% of the 300 "threats of various types" thrown at it.
Iran's Islamic Revolutionary Guard Corps, according to Israel Defense Forces spokesperson Daniel Hagari, launched 170 unmanned aerial vehicles (UAVs), more than 120 ballistic missiles and more than 30 cruise missiles in the attack.
Hagari said "99% of the threats launched towards Israeli territory were intercepted -- a very significant strategic achievement."
Hagari said the attack resulted in only one known Israeli casualty, a 7-year-old girl who was severely injured when she was struck by shrapnel apparently from an intercepted missile.
Harris to meet with American hostages' families on Tuesday
Vice President Kamala Harris will meet with the families of American hostages being held by Hamas on Tuesday afternoon, according to the White House.
Harris will "express her continued support for these families and the hostages and will provide an update on our administration’s efforts to broker a deal to secure the release of all hostages and an immediate cease-fire," a White House official said.
National security adviser Jake Sullivan met with the families on Monday.
The families told Sullivan they were appreciative of the Biden administration’s support, but also disappointed that a deal still hadn’t been reached to bring home the remaining hostages, which include eight American-Israeli citizens, the Hostages Families Forum Headquarters said.
The families said they told Sullivan they’re worried their loved ones will be the next to die if the negotiators don’t reach a deal soon.
-ABC News’ Justin Gomez
Israel says IDF killed head of Hamas' Emergency Bureau
The Israel Defense Forces said its fighter jets struck and killed Hatem Alramery, the head of Hamas' Emergency Bureau, in Gaza on Monday night.
Hamas said civilians were also killed in the strike.
Hamas says Israel is being 'stubborn' in negotiations
Hamas officials are accusing the Israelis of being "stubborn" during the latest round of negotiations in Cairo.
"Despite this," Hamas officials said in a statement, Hamas leaders are "studying the submitted proposal … and will inform the mediators of its response once this is completed."
CIA Director Bill Burns presented a new hostage/cease-fire proposal in Cairo this weekend, which included an initial release of 40 hostages in exchange for six-week cease-fire, a source familiar with the negotiations told ABC News.
CIA director presented new hostage-release deal: Source
A source tells ABC News that CIA Director William J. Burns presented a new hostage-release/cease-fire proposal in Cairo last weekend to help broker a deal between Israel and Hamas.
The source confirmed the proposal included an initial release of 40 hostages in exchange for a six-week cease-fire.
Officially, the CIA did not provide a comment.
-ABC News’ Cindy Smith and Ellie Kaufman
Israel says Iran fired dozens of drones
Iran has launched dozens of drones toward Israel, but it could take hours for them to reach, according to Israel Defense Forces spokesperson Daniel Hagari.
Israel is closing down its airspace after midnight local time and Israel's defense systems are deployed, according to Prime Minister Benjamin Netanyahu.
"We are prepared for any scenario, both in defense and attack," Netanyahu said in a video statement.
"The IDF is on high alert and is constantly monitoring the operational situation. The IDF Aerial Defense Array is on high alert, along with IAF fighter jets and Israeli Navy vessels that are on a defense mission in Israeli airspace. The IDF is monitoring all targets," the IDF said in a statement.
"We ask the public to adhere to and follow the instructions of the Home Front Command and the official IDF announcements regarding the matter," the statement added.