Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes
The IDF says it struck military targets of terrorist organizations in Gaza.
Israel launched a retaliatory strike against Iran early Friday morning local time, a senior U.S. official told ABC News.
The strike followed Iran's attack on Saturday, when Tehran sent a volley of more than 300 drones and missiles toward targets in Israel, according to Israeli military officials. All but a few were intercepted by Israel and its allies, including the United States, officials said.
Iran's weekend attack came more than six months after Hamas terrorists invaded Israel on Oct. 7, after which the Israeli military began its bombardment of Gaza.
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What to know about Iran's attack on Israel
Israeli officials said the country's Iron Dome defense system endured a big test from Iran's attack on Saturday, intercepting 99% of the 300 "threats of various types" thrown at it.
Iran's Islamic Revolutionary Guard Corps, according to Israel Defense Forces spokesperson Daniel Hagari, launched 170 unmanned aerial vehicles (UAVs), more than 120 ballistic missiles and more than 30 cruise missiles in the attack.
Hagari said "99% of the threats launched towards Israeli territory were intercepted -- a very significant strategic achievement."
Hagari said the attack resulted in only one known Israeli casualty, a 7-year-old girl who was severely injured when she was struck by shrapnel apparently from an intercepted missile.
UK prime minister 'gravely concerned' about humanitarian situation in Gaza
U.K. Prime Minister Rishi Sunak spoke on the phone with Israeli Prime Minister Benjamin Netanyahu on Tuesday. While Netanyahu thanked Sunak for the U.K.'s support to counter Iran's weekend attack on Israel, Sunak also had harsh words for Netanyahu about the deepening humanitarian crisis in Gaza.
"On Gaza, the Prime Minister said he remained gravely concerned about the deepening humanitarian crisis," a Downing Street spokesperson said. "The U.K. wanted to see a massive step change in aid access to flood Gaza with vital supplies, including Israel opening up new aid routes as quickly as possible. The Prime Minister said it was deeply disappointing that Hamas blocked a deal at the weekend that would have saved Palestinian lives and secured the safe release of hostages."
Israeli war cabinet meeting ends again with no final decision on response: Source
Prime Minister Benjamin Netanyahu's war cabinet met for the third day in a row on Tuesday to consider an Israeli response to Iran's weekend attack.
But Tuesday’s meeting ended with no final decision made about an Israeli response, according to an Israeli source with knowledge of the meeting. A variety of options are still being considered, the source said.
Iran foreign minister says 'no intention of further escalating the situation'
Iranian Foreign Minister Hossein Amir-Abdollahian told Chinese Foreign Minister Wang Yi on a call that "Iran is willing to exercise restraint and has no intention of further escalating the situation," according to the Chinese foreign ministry’s readout of the conversation.
More than 19,000 children orphaned in Gaza
Over 10,000 women have been killed in Gaza during the war, according to a report from UN Women, the United Nations’ entity for gender equality and women's empowerment.
Out of those 10,000 women, 6,000 were mothers, who have left behind 19,000 orphaned children, according to the report.
-ABC News’ Kori Skillman
'No higher priority': Harris meets with American hostages' families
During a meeting at the White House on Tuesday with the families of Americans being held hostage by Hamas, Vice President Kamala Harris said there is "no higher priority than reuniting the hostages with their loved ones," according to a White House readout.
Harris also reaffirmed the United States' commitment to bringing home the remains of those hostages who have been confirmed dead, according to the readout.
Rachel Goldberg-Polin, whose 23-year-old son Hersh is being held hostage by Hamas, described the meeting with Harris as "very productive."
“There is a possibility of holding two truths,” Goldberg-Polin told reporters outside the White House. “You can believe, as we do, that it is horrible that innocent civilians in Gaza are suffering, and at the same time you can also know that it is horrible and against international law for hostages to be held against their will."
Goldberg-Polin said her son got his arm blown off during Hamas' attack at the Nova Music festival on Oct. 7. Her husband, Jonathan Polin, said that they "have no choice but to stay hopeful."
Jonathan Dekel-Chen, the father of American hostage Sagui Dekel-Chen, called on Hamas to reach a deal to release the hostages.
"We are waiting now and the world waits for Hamas to get to yes," Dekel-Chen told reporters. "It is in their court."
-ABC News' Juhi Doshi