Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes
The IDF says it struck military targets of terrorist organizations in Gaza.
Israel launched a retaliatory strike against Iran early Friday morning local time, a senior U.S. official told ABC News.
The strike followed Iran's attack on Saturday, when Tehran sent a volley of more than 300 drones and missiles toward targets in Israel, according to Israeli military officials. All but a few were intercepted by Israel and its allies, including the United States, officials said.
Iran's weekend attack came more than six months after Hamas terrorists invaded Israel on Oct. 7, after which the Israeli military began its bombardment of Gaza.
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What to know about Iran's attack on Israel
Israeli officials said the country's Iron Dome defense system endured a big test from Iran's attack on Saturday, intercepting 99% of the 300 "threats of various types" thrown at it.
Iran's Islamic Revolutionary Guard Corps, according to Israel Defense Forces spokesperson Daniel Hagari, launched 170 unmanned aerial vehicles (UAVs), more than 120 ballistic missiles and more than 30 cruise missiles in the attack.
Hagari said "99% of the threats launched towards Israeli territory were intercepted -- a very significant strategic achievement."
Hagari said the attack resulted in only one known Israeli casualty, a 7-year-old girl who was severely injured when she was struck by shrapnel apparently from an intercepted missile.
Israel not likely to carry out strike until after Passover: US official
Israel is unlikely to carry out a strike on Iran until after Passover, a senior U.S. official told ABC News, although that could always change.
Passover begins on Monday and ends after nightfall on April 30.
The Iranian Islamic Revolutionary Guard Corps and other leadership are still on a high state of alert, with some in safe houses and underground facilities, the official said.
Israel aborted strikes against Iran 2 nights this week: Sources
Israel prepared for and then aborted retaliatory strikes against Iran on at least two nights this past week, three Israeli sources told ABC News.
Iran attacked Israel with more than 300 drones and missiles on Saturday night into Sunday morning local time in Israel. Israel has been weighing how and when to respond to Iran's attack since then, holding war cabinet meetings on Sunday, Monday and Tuesday.
The members of the Israeli war cabinet are Israeli Prime Minister Benjamin Netanyahu, Minister Benny Gantz and Defense Minister Yoav Gallant.
A range of responses have been presented to the Israeli war cabinet. The potential responses include options ranging from attacking Iranian proxies in the region but not on Iranian soil to a potential cyber attack, sources told ABC News.
There was no war cabinet meeting on Wednesday, but Netanyahu told his government cabinet that while he appreciates the advice from allies, Israel will "make our own decisions, and the State of Israel will do everything necessary to defend itself."
-ABC News' Matt Gutman and Jordana Miller
Iranian president: Israel invasion would be met with 'massive' response
Iranian President Ebrahim Raisi said at an army parade Wednesday that "the tiniest invasion" from Israel will be met with a "very massive and harsh response."
House GOP package totals $14.1 billion for Israel
House Republicans have posted the legislative text for three national security bills, addressing Ukraine, Israel and the Indo-Pacific.
For Israel, lawmakers have crafted a package totaling $14.1 billion, including: $4 billion for missile defense; $1.2 billion for Iron Beam; $4 billion replenishment of stocks to the Department of Defense; and $3.5 billion for Israel to purchase U.S. weapons.
"The House must pass the package this week and the Senate should quickly follow," President Joe Biden said in a statement. "I will sign this into law immediately to send a message to the world: We stand with our friends, and we won’t let Iran or Russia succeed."
Votes are expected in the House on Thursday, Friday and Saturday.
Sullivan to meet with hostage families on Monday
National security adviser Jake Sullivan will meet families of hostages at the White House on Monday, which is one day after the war reaches the six-month mark, a senior administration official said.
President Joe Biden on Friday wrote letters to the president of Egypt and the emir of Qatar on the state of the talks, and he urged them to secure commitments from Hamas to agree to and abide by a deal, the official added.
"The president made clear that everything must be done to secure the release of hostages, including American citizens, now held by Hamas terrorists for nearly six months," the senior administration official said.
"They discussed the importance of fully empowering Israeli negotiators to reach a deal, which in its first phase would secure the release of women, elderly, sick and wounded hostages," the official said.
A new round of talks will take place this weekend in Cairo.
-ABC News’ Selina Wang