Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes
The IDF says it struck military targets of terrorist organizations in Gaza.
Israel launched a retaliatory strike against Iran early Friday morning local time, a senior U.S. official told ABC News.
The strike followed Iran's attack on Saturday, when Tehran sent a volley of more than 300 drones and missiles toward targets in Israel, according to Israeli military officials. All but a few were intercepted by Israel and its allies, including the United States, officials said.
Iran's weekend attack came more than six months after Hamas terrorists invaded Israel on Oct. 7, after which the Israeli military began its bombardment of Gaza.
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What to know about Iran's attack on Israel
Israeli officials said the country's Iron Dome defense system endured a big test from Iran's attack on Saturday, intercepting 99% of the 300 "threats of various types" thrown at it.
Iran's Islamic Revolutionary Guard Corps, according to Israel Defense Forces spokesperson Daniel Hagari, launched 170 unmanned aerial vehicles (UAVs), more than 120 ballistic missiles and more than 30 cruise missiles in the attack.
Hagari said "99% of the threats launched towards Israeli territory were intercepted -- a very significant strategic achievement."
Hagari said the attack resulted in only one known Israeli casualty, a 7-year-old girl who was severely injured when she was struck by shrapnel apparently from an intercepted missile.
No damage to Iran’s nuclear sites after Israeli strike: IAEA
Iran's nuclear sites have not been damaged by Israel's strike on Iran early Friday morning, according to the International Atomic Energy Agency (IAEA).
In a statement released on social media, IAEA chief Rafael Grossi says he "continues to call for extreme restraint from everybody and reiterates that nuclear facilities should never be a target in military conflicts."
Flight operations resume in Iran: State media
After suspending flights at several airports following reports of an explosion in Iran, Iranian state media said early Friday normal operations have resumed.
-ABC News' Will Gretsky
Flights to Tehran, Isfahan and Shiraz suspended after reports of explosion in Iran: Iranian state media
Flights to Tehran, Isfahan and Shiraz have been suspended following reports an explosion was heard in the city of Qahjavaristan, Iranian state media reported.
The city of Qahjavaristan is located near Isfahan Airport and the 8th Shekhari Base of the Army Air Force in the northwest of Isfahan.
-ABC News' Will Gretsky
Israeli missiles have hit a site in Iran
A U.S. official confirmed to ABC News Israeli missiles have hit a site in Iran. The official could not confirm whether Syria and Iraq sites were hit as well.
-ABC News' Martha Raddatz
US sanctions 16 people, 2 groups after Iran attacks
The U.S. is sanctioning two groups and 16 people it says enabled Iran's drone production following Iran's attack on Israel last weekend.
"Today, in coordination with the United Kingdom and in consultation with partners and allies, we are taking swift and decisive action to respond to Iran’s unprecedented attack on Israel," Treasury Secretary Janet Yellen said. "We’re using Treasury’s economic tools to degrade and disrupt key aspects of Iran’s malign activity, including its UAV program and the revenue the regime generates to support its terrorism."
The Treasury Department said it’s sanctioning Khuzestan Steel Company, Iran's largest steel producer. The Treasury Department said Iran's metals sector generates "several billion dollars in revenue annually."
The U.S. is also targeting the Iranian carmaker Bahman Group for its role in making vehicles used by the Islamic Revolutionary Guard Corps for military operations.
The sanctions also target people who work for Iran-based drone manufacturers, including executives of the Mado Company, which the U.S. says produced drone engines used in Iran's Shahed UAVs. The U.S. also sanctioned members of the IRGC who it says help supply proxy groups, like the Houthis in Yemen, with drones that have attacked U.S. service members in the Red Sea.
Yellen added that the U.S. would "continue to deploy" sanctions to counter any further action by Iran, with the goal of making it harder and more expensive for Iran to undertake destabilizing actions.
President Joe Biden said in a statement that these sanctions are "holding Iran accountable."
Biden emphasized that the sanctions are in coordination with the international community, and he said the other G7 countries are committed to increasing "economic pressure" on Iran alongside the U.S.
Biden said he has instructed his team to continue to impose sanctions that will degrade Iran's military capabilities.
Biden also reiterated his ironclad support for Israel, and issued a warning to Iran and those who "enable" Iran's attacks.
"We are committed to the security of our personnel and partners in the region," Biden said. "And we will not hesitate to take all necessary action to hold you accountable."
-ABC News’ Michelle Stoddart and Justin Gomez