Police in New York, where there are locations sensitive to both Israeli and Palestinian interests, are adjusting patrols in response to the situation in Israel.

"The NYPD's Counterterrorism and Intelligence Division consistently work at a level of high alert. When events from around the world could possibly affect NYC or we get Intel on a threat to NYC, we always increase our presence around houses of worship and certain areas when these conflicts arise," the NYPD said in a statement.

The Beverly Hills Police Department also said it increased security and patrols around Jewish institutions in the City and continues to work closely with law enforcement partners in the region to ensure public safety.

Law enforcement and Homeland Security officials will be assessing the potential for residual violence in the U.S.

Increased security around Jewish facilities and on university campuses -- particularly where there is a history of confrontational interactions -- is to be expected. Increased attention is expected to be paid to potential cyber threats and online activities intended to inspire violence by Iran, Hezbollah and other extremists threat actors.

-ABC News' Aaron Katersky and Alex Stone

United Airlines, American Airlines and Delta Airlines announced they will suspend operations to Israel Saturday night following unrest in the region. After two departures scheduled for Saturday, United's future operations will be suspended until conditions allow them to resume, the airline said.

"The safety of our customers and crew is our top priority. We are closely monitoring the situation and we are adjusting flight schedules as required," the carrier told ABC News.

American Airlines said it will temporarily suspended operations to and from Tel Aviv and will continue to monitor the situation, adjusting its operations as needed.

"American Airlines has temporarily suspended operations to and from Tel Aviv, Israel (TLV) [Saturday] and [Sunday], and has issued a travel alert providing additional flexibility to customers whose travel plans are affected. We will continue to monitor the situation with safety and security top of mind and will adjust our operation as needed," American Airlines said in a statement.

Delta Air Lines has canceled scheduled flights in and out of Tel Aviv this weekend. The airline said its working to "safely transport Delta people back to the U.S. and will work with the U.S. government as needed to assist with the repatriation of U.S. citizens who want to return home."

-ABC News' Amanda Maile and Sam Sweeney

President Joe Biden spoke with Israeli Prime Minister Benjamin Netanyahu, telling him that the U.S. "condemns" Hamas' assault on Israel.

"I made clear to Prime Minister Netanyahu that we stand ready to offer all appropriate means of support to the Government and people of Israel. Terrorism is never justified. Israel has a right to defend itself and its people. The United States warns against any other party hostile to Israel seeking advantage in this situation. My Administration’s support for Israel’s security is rock solid and unwavering," Biden said in a statement.

Biden also extended his condolences for lives lost and wished those wounded a "swift recovery."

"My team and I are tracking this situation closely, and I will remain in close touch with Prime Minister Netanyahu," Biden said.

U.S. Secretary of State Antony Blinken issued a statement condemning Hamas' attack on Israel, saying the U.S. will "remain in close contact with our Israel partners."

"The United States unequivocally condemns the appalling attacks by Hamas terrorists against Israel, including civilians and civilian communities. There is never any justification for terrorism. We stand in solidarity with the government and people of Israel, and extend our condolences for the Israeli lives lost in these attacks," Blinken said in a statement.

-ABC News' Shannon Crawford

At a press conference with the Qatari prime minister, Secretary of State Antony Blinken discussed efforts to implement safe zones in Gaza and provide other humanitarian assistance, but did not shed additional light on efforts to evacuate Americans and other foreign nationals ahead of a potential Israeli ground incursion.

"When it comes to providing for civilians in Gaza, both ensuring that they can be out of harm's way and that they can have access to the support that they need -- the humanitarian assistance the food, the medicine, water -- our focus now is on helping to create safe zones. And we're doing that with leading international organizations, and we're doing that engaged with Israel," Blinken said.

But Blinken said that those efforts to help Palestinians were still being actively hindered by Hamas.

"Hamas continues to use innocent civilians as human shields," he said.

"We know the humanitarian situation is urgent. We're actively engaged with partners, including Qatar, to get aid to the those who need it," he said.

-ABC News' Shannon Crawford