A United Nations worker was killed and another injured after their vehicle was struck in Gaza on Monday, the organization said.

The staff members of the U.N. Department of Safety and Security were traveling to the European Hospital in Rafah when their U.N. vehicle was struck, the U.N. said.

Details on the incident were not immediately available. The U.N. said it is still gathering information.

U.N. Secretary-General António Guterres has called for a full investigation, his spokesperson said.

"Humanitarian workers must be protected," Guterres said on X. "I condemn all attacks on U.N. personnel and reiterate my urgent appeal for an immediate humanitarian ceasefire & the release of all hostages."

More than 190 U.N. staff members have been killed in Gaza since Oct. 7, according to Guterres.

Almost 360,000 people have fled from the southern Gazan city of Rafah since Israel issued an evacuation order last week, the United Nations agency operating in Gaza said on Monday.

"There's nowhere to go," the U.N. Agency for Palestine Refugees said on social media. "There's NO safety without a cease-fire."

The agency had said Sunday that 300,000 people had evacuated the city as Israel weighs a full-scale invasion.

-ABC News' Kevin Shalvey

The Israel Defense Forces has announced that it has opened a new crossing to bring humanitarian aid into the famine-stricken Gaza.

The military announced in a Sunday press release the opening of the Western Erez crossing between Israel and northern Gaza in coordination with the U.S.

According to the military, the new crossing is located west of the Erez crossing, closer to the seashore. The crossing was constructed by the Israeli military "as part of the effort to increase routes for aid to Gaza, particularly to the North of the strip."

Earlier Sunday, IDF said it launched a large-scale operation in the area of Jabaliya in the North, while intensifying its military operations in the Eastern portion of Rafah and the Gaza side of the Rafah crossing. It said that it had called on the civilian population to evacuate from Jabaliya to shelters in the west part of Gaza City.

-ABC News' Dragana Jovanovic

In a phone call Sunday with his Israeli counterpart, White House National Security Advisor Jake Sullivan expressed an "ironclad U.S. commitment" to Israel but also voiced the Biden administration's concerns about Israel's major military operations in Gaza, according to the White House.

During the call with Israeli National Security Advisor Tzachi Hanegbi, Sullivan reiterated President Joe Biden's "longstanding concerns over the potential for a major military ground operation into Rafah, where over one million people have taken shelter," according to a readout of the call that was released by the White House.

"He [Sullivan] discussed alternative courses of action to ensure the defeat of Hamas everywhere in Gaza," the readout said. "Mr. Hanegbi confirmed that Israel is taking U.S. concerns into account."

The White House said Sullivan also expressed condolences on Israel's Memorial Day, the first since Hamas' surprise Oct. 7 attacks on Israel. The Hamas attack killed 1,200 people, most of them civilians, according to Israel's Prime Minister's Office.

Sullivan and Hanegbi also reviewed discussions by officials on both sides of the war about alternatives for a Rafah invasion and agreed to plan an in-person meeting soon, according to the White House.

-ABC News' Michelle Stoddart

About 450,000 Palestinians have been displaced from Rafah, fleeing to safety, according to the U.N. Relief and Works Agency for Palestine Refugees in the Near East.

"Inland in Rafah is now a ghost town. It’s hard to believe there were over one million people sheltering here just a week ago,” UNRWA spokesperson Louise Wateridge said. "People face constant exhaustion, hunger and fear. Nowhere is safe. An immediate ceasefire is the only hope."

The development comes as airstrikes continued to hit northern and southern Gaza Tuesday. The Israeli military said it had hit 120 targets in the last 24 hours.

-ABC News' Will Gretsky