A man in Tel Aviv has died after being injured in an explosion resulting from what authorities believe was an unmanned aerial vehicle (UAV).

"During searches of the scene, an unconscious man was found in one of the buildings, with penetrating injuries," Zachi Heller, a spokesperson for Israel's emergency medical service Magen David Adom (MDA), confirmed to ABC News.

The man, who Heller said was 50, did not exhibit signs of life and it was determined he had died.

Information is still developing, but the Israel Defense Forces said early Friday morning that the person who died was hit by a fragment of the UAV.

IDF Chief spokesperson Rear Admiral Daniel Hagari said the military assessed that the drone was an upgraded Iranian-made Samad-3 model.

"Our estimation is that it arrived from Yemen to Tel Aviv," he told a briefing with journalists.

Four people were treated for shrapnel injuries at the scene and four were treated by EMS for shock/anxiety. All eight were taken to the Wolfson and Ichilov hospitals, Heller said.

-ABC News' Will Gretsky

Two people were injured in a blast in Tel Aviv early Friday morning local time, Israel's emergency medical service, Magen David Adom (MDA) confirmed.

Emergency services received a report at 3:12 a.m. that an object had exploded in Tel Aviv. After arriving on the scene, medics transported a 37-year-old man and a 25-year-old woman in mild condition to Ichilov Hospital. The victims had "shrapnel injuries to the limbs and shoulder," MDA spokesman Zachi Heller said. Four additional victims were treated for shock/anxiety.

Following the incident report, five fire crews arrived and extinguished the fire. They are currently conducting searches in the area.

A United States official confirmed to ABC News that the explosion had occurred near the U.S. embassy branch office in Tel Aviv, but the building was not damaged. The official said that the cause of the blast is still being assessed and that the office is advising American citizens in Tel Aviv to shelter in place.

The Israel Defense Forces said it was unaware that an unmanned aerial vehicle infiltrated Israel's defenses. The IDF is currently reviewing the incident.

-ABC News' Will Gretsky and Shannon Kingston

Poliovirus has been detected in sewage samples in the Gaza Strip according to testing conducted in coordination with the United Nations, the Gaza Ministry of Health announced Thursday.

Samples were taken from sewage water that "collects and flows between the tents of the displaced and in the places where residents are located as a result of the destruction of the infrastructure" in war-torn Gaza, according to the ministry.

"The presence of the virus that causes polio ... represents a new health disaster," the ministry said in a statement. "There is severe overcrowding, a scarcity of available water and its contamination with sewage water, the accumulation of tons of garbage and the occupation's prevention of the entry of hygiene materials, which creates a suitable environment for the spread of various epidemics."

The ministry called for "an immediate halt to the Israeli aggression, the provision of usable water, the repair of sewage lines and an end to the overcrowding at displacement camps."

Polio, or poliomyelitis, is an infectious disease caused by the poliovirus, which attacks the nervous system and can lead to irreversible paralysis, according to the World Health Organization.

Polio mainly affects children under 5, though the virus can strike at any age. It’s incurable but completely vaccine-preventable. The virus is highly contagious and can live for weeks in an infected person's feces, which can contaminate food and water in unsanitary conditions and spread to other people. Polio remains endemic in two countries: Afghanistan and Pakistan, according to the WHO.

-ABC News' Morgan Winsor

At least two people were killed and five others were injured after Israel carried out a strike on Al-Falah School in Al-Zaytoun neighborhood, the ninth school the IDF has targeted in the last 10 days, according to the Gaza Civil Defense.