Asked at a transition event in Wilmington, Delaware, about whether House Democrats should introduce articles of impeachment against Trump as soon as Monday -- just over a week from when Biden is slated to take office, Biden had a lengthy answer about how he's focused on the pandemic and leaving that decision to Congress.

"Look, I’ve thought for a long, long time that President Trump wasn’t fit to hold the job. That’s why I ran. And my job now, in 12 days -- God willing, I’ll be President of the United States of America. And I’m focused on the urgency of three immediate concerns," Biden said, "the virus, the vaccine and economic growth."

"What the Congress decides to do is for them to decide, but I'm going to have to -- and they're going to have to be ready -- to hit the ground running, because when Kamala and I are sworn in, we're gonna be introducing immediately significant pieces of legislation to deal with the virus, deal with the economy and deal with economic growth," he continued. "So we're going to do our job, and the Congress can decide how to proceed with theirs."

Asked what he would say if a Democratic member of Congress were to ask his advice about whether they should proceed, Biden said he'd deflect.

"I’d tell them that's a decision for the Congress to make. I'm focused on my job," he said.

Pressed on whether he spoke with House Speaker Nancy Pelosi before taking this stance, Biden said they will be speaking later on "about my agenda as well as whatever they want to talk to me about."

Biden, in announcing Cabinet nominees for key economic and jobs positions, confirmed he gave "serious consideration" to nominating Vermont Sen. Bernie Sanders for secretary of labor, but he said the two agreed they couldn't risk Republicans gaining control of the Senate.

"He could have done a fantastic job. I can think of no more passionate and devoted ally to working people in this country. But after Tuesday's results in Georgia, giving Democratic control of the United States Senate in a tie vote, Bernie and I agreed -- as a matter of fact, Bernie suggested -- we can't put control of the Senate at risk on the outcome of a special election in Vermont," Biden said.

Biden also reiterated in his remarks he supports raising the minimum wage to $15, passing more coronavirus relief legislation to small business owners and releasing more COVID-19 vaccine doses immediately to Americans to administer as many shots as possible.

Sen. Patty Murray, D-Wash., has called on Sen. Ted Cruz, R-Texas, and Josh Hawley, R-Mo., to resign in the aftermath of the violent siege on the Capitol, accusing the Republican senators of inciting the pro-Trump mob that stormed into the building.

“As a Senator, I respect every member who disagrees with my ideas. I reserve my right to use my voice to fight for what I believe in. But at the end of the day, our job is to keep this country a democracy where voices win, not brute force," Murray wrote in a statement.

"Any Senator who stands up and supports the power of force over the power of democracy has broken their oath of office. Senators Hawley and Cruz should resign,” she added.

Hawley and Cruz led challenges to Wednesday's Electoral College ratification, which repeated Trump's unsubstantiated claims of voter fraud in the 2020 presidential election

Murray is the highest-ranking Senate Democrat to urge for the senators' resignations. Her statement echoes similar calls for Cruz and Hawley to step down from Sen. Chris Coons, D-Del., and Rep. Alexandra Ocasio-Cortez, D-N.Y.

Vice President Mike Pence arrived at the White House Friday afternoon, after spending Thursday away from the White House complex.

Pence will be participating in meetings and calls at the White House and planned to stop by his office’s weekly staff meeting, according to his office.

The vice president’s office did not respond to questions about whether Pence planned to meet with Trump amid calls from Democrats for Pence to invoke the 25th Amendment.

Pence remained at his residence at the Naval Observatory grounds in Washington all day Thursday, according to a senior administration official, and received his second dose of the COVID-19 vaccine, his office said Thursday.

-ABC News' Ben Gittleson and Elizabeth Thomas

House Speaker Nancy Pelosi, in a new letter to Democrats on Saturday, asked members to prepare to return to Washington this week -- another signal that the House could take up and pass the impeachment article to the Senate after it is formally introduced on Monday.

Pelosi thanked fellow Democratic representatives for speaking with her on a conference call Friday and said she was taking their considerations into account. She did not specifically mention voting on impeachment in the letter, though.

"Since that call, I have received scores of communications from Members expressing your views about how we go forward and regarding a strong presence of our Caucus in the Capitol," she wrote. "Over the last few days, I have discussed your views with Constitutional lawyers, both inside and outside the Congress, to consider the parliamentary and constitutional options available to us."

"From what I have heard from Members, and from the deluge that I have received from the public, it is clear that, once again, the Times Have Found Us to save our democracy," Pelosi added in the letter. "We will be proceeding with meetings with Members and Constitutional experts and others. I continue to welcome your comments. I urge you to be prepared to return to Washington this week."

While Democrats are hopeful Republicans will back their effort, none have come out and said they would back the charge as drafted.

Pelosi said at a press conference on Thursday, "If the Vice President and Cabinet do not act [on the 25th Amendment], the Congress may be prepared to move forward with impeachment."

Some Democrats planned to connect with Republican colleagues this weekend to gauge their support and encourage them to back the effort.

-ABC News' Benjamin Siegel