Before introducing his Justice Department picks from Wilmington, Delaware, on Thursday, Biden offered comments on Wednesday's chaos at the Capitol which he deemed "one of the darkest days in the history of our nation" and "an unprecedented assault on our democracy."

"All of us here grieve the loss of life, grieve the desecration of the people's house. But what we witnessed yesterday was not dissent. It was not disorder. It was not protests. It was chaos," Biden said. "They weren't protesters. Don't dare call them protesters. They were a riotous mob, insurrectionists, domestic terrorists."

Biden placed blame on Trump who, he said, for the past four years has "made his contempt for our democracy, our Constitution, the rule of law clear in everything he has done."

"He unleashed an all-out assault on our institutions of our democracy from the outset. And yesterday was but the culmination of that unrelenting attack," Biden said.

Biden also predicted the response would have been very different had the majority of rioters been Black.

"No one can tell me that if it had been a group of Black Lives Matter protesting yesterday, there wouldn't have been -- they would have been treated very, very differently than the mob of thugs that stormed the Capitol. We all know that's true, and it is unacceptable, totally unacceptable," he said.

House Speaker Nancy Pelosi has called on Vice President Mike Pence to invoke the 25th Amendment to remove Trump from office for his "seditious acts" following Wednesday's rioting at the Capitol, she said at a press conference Thursday.

The California Democrat is threatening impeachment proceedings if Pence does not.

-ABC News' Mariam Khan

Senate Majority Leader Mitch McConnell put out a statement Thursday, saying the riots within the Capitol Building Wednesday represent "a massive failure" of "institutions, protocols, and planning that are supposed to protect the first branch of our federal government."

"A painstaking investigation and thorough review must now take place and significant changes must follow," McConnell added. "Initial bipartisan discussions have already begun among committees of oversight and Congressional Leadership."

-ABC News' Allison Pecorin

Transportation Secretary Elaine Chao is resigning from her position in the wake of rioting at the U.S. Capitol.

She cites the storming of the Capitol by "supporters of the President" as an "entirely avoidable event" in a letter she is sending out to her colleagues announcing her resignation.

"Yesterday, our country experienced a traumatic and entirely avoidable event as supporters of the President stormed the Capitol building following a rally he addressed. As I'm sure is the case with many of you, it has deeply troubled me in a way that I simply cannot set aside," Chao said.

Chao is married to Senate Majority Leader Mitch McConnell.

House Speaker Nancy Pelosi, in a new letter to Democrats on Saturday, asked members to prepare to return to Washington this week -- another signal that the House could take up and pass the impeachment article to the Senate after it is formally introduced on Monday.

Pelosi thanked fellow Democratic representatives for speaking with her on a conference call Friday and said she was taking their considerations into account. She did not specifically mention voting on impeachment in the letter, though.

"Since that call, I have received scores of communications from Members expressing your views about how we go forward and regarding a strong presence of our Caucus in the Capitol," she wrote. "Over the last few days, I have discussed your views with Constitutional lawyers, both inside and outside the Congress, to consider the parliamentary and constitutional options available to us."

"From what I have heard from Members, and from the deluge that I have received from the public, it is clear that, once again, the Times Have Found Us to save our democracy," Pelosi added in the letter. "We will be proceeding with meetings with Members and Constitutional experts and others. I continue to welcome your comments. I urge you to be prepared to return to Washington this week."

While Democrats are hopeful Republicans will back their effort, none have come out and said they would back the charge as drafted.

Pelosi said at a press conference on Thursday, "If the Vice President and Cabinet do not act [on the 25th Amendment], the Congress may be prepared to move forward with impeachment."

Some Democrats planned to connect with Republican colleagues this weekend to gauge their support and encourage them to back the effort.

-ABC News' Benjamin Siegel