Harris struggled to find her role in the first few years of the Biden administration, but began to shine when talking about the fight for reproductive rights after the fall of Roe v. Wade.

"Let's be clear about how we got here, Donald Trump hand picked members of the United States Supreme Court to take away reproductive freedom, and now he brags about it," she said.

She then turned her ire to Republicans in Congress.

"Why exactly is it that they don't trust women?" she said. "Well, we trust women."

Second gentleman Doug Emhoff, seated with his children and Harris' sister Maya, was seen wiping his eyes after Harris walked out to the lectern. He was the first person to receive a shout-out from the vice president, who remarked on their 10th wedding anniversary.

Her running mate, Tim Walz, was also looking on with emotion as she took the stage.

Harris discussed the controversial "Project 2025" conservative policy proposals contending that would mean "Donald Trump with no guardrails."

"He would use the immense powers of the presidency of the United States not to improve your life, not to strengthen our national security, but to serve the only client he has ever had: himself," she said.

"Its sum total is to pull our country back to the past," Harris said of "Project 2025. "But America, we are not going back."

After proclaiming, "America, we are not going back," the crowd erupted into chants of "we're not going back."

The chants got so loud that at first, you couldn't hear Harris over the speakers.