In a bit of counterprogramming, President Joe Biden's campaign has released a set of questions it suggests the moderators ask of his potential opponents on Wednesday. The first: “Do you support Donald Trump’s plans to be a dictator on day 1?"

The campaign’s press release is a response to former President Trump’s comment on Tuesday that, “except for Day One,” he wouldn’t be a “dictator” if he returned to the presidency. “No, no, no. Other than day one. We’re closing the border, and we’re drilling, drilling, drilling. After that, I’m not a dictator,” the Republican front-runner told Fox News’ Sean Hannity.

The campaign, seeking to make democracy a central issue in next year's race, also suggested DeSantis, Haley, Ramaswamy and Christie speak to another democratic norm: “Will you accept the results of the 2024 election unequivocally?"

-ABC News' Chris Boccia

Will a smaller stage make a difference? What will the big policy topics be? Do DeSantis and Haley target Trump ... or each other?

Those are three of five notable things to watch in the fourth debate, on Wednesday night.

Read more about them here.

-ABC News' Tal Axelrod

It's been four weeks since Republican primary contenders last met on stage. A lot has happened between then and now.

Two candidates dropped out of the race: South Carolina Sen. Tim Scott and North Dakota Gov. Doug Burgum.

Their exits whittled down the field down to five major candidates, though Trump remains the front-runner with two candidates now vying for second place in the polls: DeSantis and Haley. All three recently received notable endorsements with voting just weeks away. The Koch-backed group Americans for Prosperity Action threw its support behind Haley over Trump while DeSantis has earned key endorsements in Iowa, including from Gov. Kim Reynolds and Trump, despite his absence, just got the backing of Alabama Sen. Katie Britt.

This is the last chance for candidates to get a boost on the national stage before next month's Iowa caucuses and the New Hampshire primary.

-ABC News' Alexandra Hutzler

The debate, being held at the University of Alabama in Tuscaloosa, will air on cable news network NewsNation at 8 p.m. EST.

It will also be broadcast in the Eastern and Central time zones on the company's broadcast television network, The CW.

The faceoff will be livestreamed on NewsNation's website and on Rumble as well.

The moderators will be Elizabeth Vargas, the anchor of NewsNation's "Elizabeth Vargas Reports"; Megyn Kelly, the former Fox News and NBC News anchor who now hosts "The Megyn Kelly Show" on Sirius XM; and Eliana Johnson, editor-in-chief of The Washington Free Beacon.

-ABC News' Sarah Beth Hensley

Haley and Ramaswamy -- who are both set to be on stage again -- have had multiple fiery exchanges so far in the GOP debates, and Wednesday could see more sparring.

Among their mutual jabs, during the second primary debate, in September, Haley said she felt "a little bit dumber" listening to the entrepreneur.

"TikTok is one of the most dangerous social media apps that we could have. I -- honestly, every time I hear you, I feel a little bit dumber for what you say," Haley said at one point, noting Ramaswamy's recent participation on TikTok despite his criticism of the platform.

Ramaswamy responded that the Republican Party would be better served "if we're not sitting here hurling personal insults and actually have a legitimate debate about policy."

Discussions on the social media platform prompted another notable exchange during the third debate, last month. After Ramaswamy mentioned that Haley's daughter has used TikTok, despite criticism of the Chinese-owned app, Haley lashed out.

"Leave my daughter out of your voice," she said, adding with an eye roll: "You're just scum."

Ramaswamy took another swipe at Haley during the third debate, saying, "Do you want a leader from a different generation who's going to put this country first, or do you want Dick Cheney in three-inch heels?"

Haley responded, "I'd first like to say they're five-inch heels, and I don't wear them unless you can run in them. The second thing that I will say is, I wear heels, they're not for a fashion statement -- they're for ammunition."

-ABC News' Meredith Deliso