After an expanded detention facility for child migrants reopened in Carrizo Springs, Texas, Rep. Alexandria Ocasio-Cortez, D-N.Y., tweeted Tuesday, “This is not okay, never has been okay, never will be okay - no matter the administration or party.”

In a press briefing Wednesday, Psaki attempted to cast the Biden administration’s efforts to manage immigration as a major improvement over President Donald Trump’s policies but didn’t fully address Ocasio-Cortez's criticism that such facilities shouldn’t exist at all.

Psaki said the administration had three options when it comes to child migrants: to send them back to their countries (which she said can be dangerous), to transfer them to a facility managed by the Department of Health and Human Services, or to put them in the care of families or sponsors "without any vetting." She said the administration has chosen the middle option.

“What we are doing is working as quickly as possible to process these kids into these HHS facilities, which have been revamped, which have medical and educational services available, so that we can then transfer them to families. That's what our approach is,” Psaki said.

Psaki would not commit to a request to allow media in to prove that children are treated humanely, citing privacy and security concerns. Psaki tried to explain the administration’s options in dealing with minors at the border and why the detention facilities have become a primary strategy.

“This is a difficult situation. It's a difficult choice. That's the choice we've made,” she said.

Psaki also attempted to defend delays in transferring children from facilities run by Customs and Border Protection, which often lack amenities, to Health and Human Service facilities that are intended for longer-term care. By law, children are supposed to spend no more than 72 hours in Customs and Border Protection facilities after initial apprehension.

“There were some delays last week because of weather, and because some of these facilities to safely move these kids to, did not have power and were not in a place where they could -- they had the capacity to take in these kids and do it safely. That is not our objective. That is not our goal," Psaki said. "So some, unfortunately, did stay four days, five days, or longer, but the objective is to move them as quickly as possible to the HHS sponsored facilities.”

-ABC News' Sarah Kolinovsky

In keeping with the White House's focus of the day, Biden held a bipartisan Oval Office meeting Wednesday with House and Senate members ahead of signing an executive order mandating a review of critical U.S. supply chains.

"The last year has shown the vulnerability we have with some of the supply chains, including the PPE that we needed badly but had to go abroad to get. And there are current strategies," Biden said.

Biden praised the bipartisan effort to address the shortage of the chips for cars and said the group planned to discuss the problem, along with other shortage issues.

-ABC News' Molly Nagle

The White House was surprised to discover that Johnson & Johnson will only have about 3 to 4 million doses of its vaccine ready to ship once the FDA grants an emergency use authorization, White House press secretary Jen Psaki said during a press briefing Wednesday.

Johnson & Johnson had estimated it could ship 12 million doses at the end of February in a $1 billion contract signed with the federal government in August.

“We were surprised to learn that Johnson & Johnson was behind on their manufacturing. As you noted, it was kind of reported earlier to be about 10 million, and now it's more like 3 to 4 million doses that they would be ready to ship next week if they are moved through the FDA process, which is not yet concluded, just to note," Psaki said. "And we are going to continue to work with them on ensuring that that can be expedited.”

Despite the initial availability, Johnson & Johnson has said it expects 20 million doses to be available by the end of March and to meet its contractual obligation for 100 million doses by the end of June.

-ABC News' Sarah Kolinovsky

Veteran diplomat Linda Thomas-Greenfield was sworn in Wednesday morning as Biden's U.N. ambassador. Thomas-Greenfield, known for her "gumbo diplomacy", is a Louisiana native and child of the segregated South.

After being sworn in, Thomas-Greenfield tweeted saying she was "honored" to hold the post.

"Diplomacy is back. Multilateralism is back," Thomas-Greenfield said in the tweet. "America is back."

One hundred and sixty chief executive officers sent an open letter to congressional leadership Wednesday, urging lawmakers to pass "immediate and large-scale federal legislation to address the health and economic crises brought on by the COVID-19 pandemic" on a bipartisan basis.

The letter asks Congress to "to authorize a stimulus and relief package along the lines of the Biden-Harris administration’s proposed American Rescue Plan," perhaps leaving some room for negotiation on what the final package will look like. But the letter makes clear that major business CEOs, including the heads of Morgan Stanley, Visa, United Airlines, BlackRock, Comcast and Google are pushing for relief on the scale of Biden's plan.

"The American Rescue Plan provides a framework for coordinated public-private efforts to overcome COVID-19 and to move forward with a new era of inclusive growth. The country’s business community is prepared to work with you to achieve these critical objectives," the letter says.

Just Tuesday, though, Sen. Mitt Romney, R-Utah, one of the few Senate Republicans who has shown willingness to buck his party, criticized the $1.9 trillion bill in a Wall Street Journal op-ed.

"The $1.9 trillion bill is a clunker. It would waste hundreds of billions of dollars, do nothing meaningful to get kids back to school, and enact policies that work against job creation. The Congressional Budget Office’s recent analysis of the plan found that more than a third of the proposed funding—$700 billion—wouldn’t be spent until 2022 or later, undermining the administration’s claim that the massive price tag is justified for urgent pandemic-related needs," Romney wrote.

Whether the pressure from big business will sway any Republicans in the Senate remains to be seen, but Wednesday morning's messaging from GOP lawmakers is pretty clear: They have no intentions of budging.

-ABC News' Sarah Kolinovsky