On Tuesday afternoon, the president will meet virtually with a group of Black essential workers to thank them for their critical roles during the pandemic.

Then, Biden will participate in his first bilateral meeting with Prime Minister Justin Trudeau of Canada and after give a statement on the meeting.

Three of Biden's picks for key administration positions have hearings before Senate committees Tuesday.

The Senate Energy and Natural Resources Committee will hold a hearing to consider Debra Haaland for secretary of the Interior. If the Senate confirms her as secretary of the interior, Haaland would be the first Native American to serve in a presidential Cabinet and would be the first Native person to oversee an agency that's played a major role historically in the forced relocation and oppression of Indigenous people.

The Senate Health, Education, Labor and Pension Committee will consider Xavier Becerra to serve as secretary of health and human services.

Republican opposition to Becerra has been mounting since Biden announced his nomination in December. On Monday, a group of Republican lawmakers penned a letter to Biden urging him to withdraw Becerra's nomination.

The group of lawmakers, including 11 senators and many more members of the House, argued that Becerra is inexperienced and ill-prepared to guide the agency. Democrats have argued that Becerra has extensive experience in health care policy, first as a congressman who oversaw components of Medicare and then as a defendant of Obamacare as attorney general, using that role to add new focus on the issue.

And the Senate Judiciary Committee will resume its hearing, which began Monday, to consider Merrick Garland for attorney general.

Garland received a fairly warm welcome from both sides of the aisle during Monday's hearing, and a few GOP senators expressed their support for Garland. In the first half of his confirmation hearing Monday, he told senators his first briefing once he takes office at the Justice Department will be on the Jan. 6 assault on the U.S. Capitol.

-ABC News' Cheyenne Haslett, Allison Pecorin, Luke Barr and Alexander Mallin

The U.S. Treasury announced sanctions on two more Myanmar military commanders, specifically citing the killing of three peaceful protesters in recent days.

Moe Myint Tun and Maung Maung Kyaw are both generals who were named by the military to join the state administration council, the coup’s new ruling body.

This brings the total number of sanctioned Myanmar officials to 12, and it comes days after the British and Canadian governments followed the Biden administration in sanctioning coup leaders. The European Union’s foreign affairs council announced Monday that it “stands ready to adopt restrictive measures targeting those directly responsible for the military coup and their economic interests” and review Myanmar’s trade status.

“Those directly responsible” have shown no sign of even acknowledging whatever financial pressure these penalties bring -- although it is meant as a message to the millions who have protested in recent days against the coup that the U.S. is actively watching.

Secretary of State Antony Blinken reiterated Biden’s call for the military to relinquish power, free political prisoners, and halt attacks on peaceful protests, saying Monday evening in a statement, “We will not hesitate to take further action against those who perpetrate violence and suppress the will of the people. We will not waver in our support for the people of Burma.”

-ABC News' Conor Finnegan

Following his brief speech, Biden, first lady Jill Biden, Vice President Kamala Harris and second gentleman Doug Emhoff walked out to the South Portico at the White House where candles were lit and displayed on the steps for the moment of silence.

Earlier, the National Cathedral rang its bells to honor the more than 500,000 Americans who died from the coronavirus.

"I received a letter from a daughter whose father died of COVID-19 on Easter Sunday last year," Biden said before the ceremony. "She and her children, his grandchildren, enter Lent this season, a season of reflection and renewal, with heavy hearts. Unable to properly mourn, she asked me in the letter, what was our loss among so many others? Well, that's what has been so cruel."

"So many of the rituals that help us cope, that help us honor those we loved, haven't been available to us. The final rites, with family gathered around, the proper home going, showered with stories and love, tribal leaders passing out the final traditions of sacred cultures on sacred lands," he continued. "As a nation, we cannot and we must not let this go on. That's why the day before my inauguration ... I said, 'to heal -- to heal, we must remember.' I know it's hard. I promise you, I know it's hard. I remember. But that's how you heal. You have to remember."

One hundred and sixty chief executive officers sent an open letter to congressional leadership Wednesday, urging lawmakers to pass "immediate and large-scale federal legislation to address the health and economic crises brought on by the COVID-19 pandemic" on a bipartisan basis.

The letter asks Congress to "to authorize a stimulus and relief package along the lines of the Biden-Harris administration’s proposed American Rescue Plan," perhaps leaving some room for negotiation on what the final package will look like. But the letter makes clear that major business CEOs, including the heads of Morgan Stanley, Visa, United Airlines, BlackRock, Comcast and Google are pushing for relief on the scale of Biden's plan.

"The American Rescue Plan provides a framework for coordinated public-private efforts to overcome COVID-19 and to move forward with a new era of inclusive growth. The country’s business community is prepared to work with you to achieve these critical objectives," the letter says.

Just Tuesday, though, Sen. Mitt Romney, R-Utah, one of the few Senate Republicans who has shown willingness to buck his party, criticized the $1.9 trillion bill in a Wall Street Journal op-ed.

"The $1.9 trillion bill is a clunker. It would waste hundreds of billions of dollars, do nothing meaningful to get kids back to school, and enact policies that work against job creation. The Congressional Budget Office’s recent analysis of the plan found that more than a third of the proposed funding—$700 billion—wouldn’t be spent until 2022 or later, undermining the administration’s claim that the massive price tag is justified for urgent pandemic-related needs," Romney wrote.

Whether the pressure from big business will sway any Republicans in the Senate remains to be seen, but Wednesday morning's messaging from GOP lawmakers is pretty clear: They have no intentions of budging.

-ABC News' Sarah Kolinovsky