Senate Majority Leader Chuck Schumer, in a remarkably candid moment, told reporters that during a closed-door lunch with his caucus Tuesday, he made a strong pitch for them to set aside differences over specific policies like the minimum wage hike and just vote for the president's COVID-19 relief bill.

Sen. Dick Durbin, D-Ill., then went a bit further after Schumer left the room and said the majority leader had "begged" his members to drop their opposition, emphasizing that the relief bill is Biden's signature legislation, and they need to stick together.

"He's begging all of us -- despite disagreements people may have -- this is the Administration's signature bill...And we need to stick together," Durbin recounted.

Some moderate Democrats like Sens. Joe Manchin, D-W.V., and Kyrsten Sinema, D-Ariz., have expressed concern about a $15 per hour minimum wage hike included in $1.9 trillion relief proposal. Manchin said an $11 an hour increase would be more appropriate for his state.

Republicans have hammered Democrats for forcing the increase on businesses suffering under the economic strains of the pandemic, but supporters of the wage increase -- a doubling of the current federal minimum wage -- note that the Biden plan is implemented over a five-year period.

GOP Sens. Tom Cotton of Arkansas and Utah's Mitt Romney introduced a plan Tuesday that would increase the minimum wage to $10 per hour by 2025 with a mandatory requirement that businesses implement E-Verify to ensure undocumented workers do not receive the increase.

The GOP proposal is not expected to be adopted as Democrats speed toward passage of the overall Biden plan.

-ABC News' Trish Turner

The Senate has confirmed Tom Vilsack to serve as secretary of agriculture, in a 92-7 vote.

Sen. Bernie Sanders voted with six Republicans against Vilsack, who had the same role under former President Barack Obama.

-ABC News' Benjamin Siegel

A spokesperson for Republican Leader Mitch McConnell confirmed reports to ABC News that McConnell intends to support the nomination of Merrick Garland to serve as attorney general.

McConnell's support for Garland was first reported by Politico.

The Senate Judiciary Committee on Tuesday wrapped up two days of hearings on Garland's nomination. The committee is scheduled to hold a vote on the nomination on March 1.

McConnell's support for Garland is in stark contrast to his 2016 efforts that successfully kept Garland from the Supreme Court bench.

-ABC News' Allison Pecorin

Senate Minority Leader Mitch McConnell doubled down on his position that the COVID-19 proposal from Democrats is far too large, not targeted enough and flies in the face of bipartisanship during a press conference Tuesday.

"We think this is dramatically more money than is required at this particular juncture. It also includes a number of things that have absolutely nothing to do with COVID relief," McConnel said. "And so it will be controversial."

McConnell said his conference is united Tuesday in "opposition to what the Biden administration is trying to do," arguing that Biden, who campaigned as a moderate, has been pushing far-left policies since his administration began, calling Biden's "a totally partisan approach to COVID relief."

-ABC News' Allison Pecorin

Biden and Harris will participate in an event Thursday afternoon commemorating 50 million COVID-19 vaccine shots administered during the Biden administration, which is halfway to Biden’s goal of distributing 100 million COVID-19 shots in his first 100 days in office.

When Biden set out the goal at the beginning of his term, the administration was already on pace to administer nearly 1 million vaccines a day, which some public health experts have said is not fast enough to control the pandemic.

Dr. Anthony Fauci, Biden’s chief medical adviser, has estimated that 325 million people will need to be immunized for the pandemic to end and to reach that threshold, Biden would need more vaccinations.

Biden has rejected the suggestion that his goal was too low, telling reporters in January that, "it's a good start."

Meanwhile, Harris visited a Giant supermarket in Southeast Washington, D.C. Thursday morning to promote the administration’s Federal Retail Pharmacy Program for COVID-19 vaccinations, which has delivered 1 million doses to over 6,500 pharmacies across the country.

Harris spoke to the store's pharmacist and then watched as a patient, Brenda Thompson, received her second dose of the Moderna vaccine.

Biden will also participate in the National Governors Association’s Winter Meeting Wednesday afternoon, and the White House will give a press briefing at 12:30 p.m.