National Economic Council Deputy Director Sameera Fazili and National Security Council Senior Director of International Economics and Competitiveness Peter Harrell joined a White House press briefing to discuss the executive order Biden will sign Wednesday afternoon that will commence an investigation and deliver recommendations to fix supply chain vulnerabilities revealed by the COVID-19 pandemic.

"Make no mistake, we are not simply planning to order up reports. We are going to be taking actions to close gaps as we identify them..." Harrell said.

The executive order will mandate a 100-day review of critical product supply chains in the U.S. focused on those for computer chips, large capacity batteries, active pharmaceutical ingredients and critical minerals and strategic materials, including rare earth minerals.

Fazili argued the investigation could be good for the U.S. economy.

"There are opportunities for small business development to help diversify supplier networks and alleviate the risk of too-big-to-fail companies in the supply chains for critical goods," Fazili said. "There are opportunities to improve worker readiness and training so they have the skills needed to ramp up research, production, or distribution of a critical good."

One hundred and sixty chief executive officers sent an open letter to congressional leadership Wednesday, urging lawmakers to pass "immediate and large-scale federal legislation to address the health and economic crises brought on by the COVID-19 pandemic" on a bipartisan basis.

The letter asks Congress to "to authorize a stimulus and relief package along the lines of the Biden-Harris administration’s proposed American Rescue Plan," perhaps leaving some room for negotiation on what the final package will look like. But the letter makes clear that major business CEOs, including the heads of Morgan Stanley, Visa, United Airlines, BlackRock, Comcast and Google are pushing for relief on the scale of Biden's plan.

"The American Rescue Plan provides a framework for coordinated public-private efforts to overcome COVID-19 and to move forward with a new era of inclusive growth. The country’s business community is prepared to work with you to achieve these critical objectives," the letter says.

Just Tuesday, though, Sen. Mitt Romney, R-Utah, one of the few Senate Republicans who has shown willingness to buck his party, criticized the $1.9 trillion bill in a Wall Street Journal op-ed.

"The $1.9 trillion bill is a clunker. It would waste hundreds of billions of dollars, do nothing meaningful to get kids back to school, and enact policies that work against job creation. The Congressional Budget Office’s recent analysis of the plan found that more than a third of the proposed funding—$700 billion—wouldn’t be spent until 2022 or later, undermining the administration’s claim that the massive price tag is justified for urgent pandemic-related needs," Romney wrote.

Whether the pressure from big business will sway any Republicans in the Senate remains to be seen, but Wednesday morning's messaging from GOP lawmakers is pretty clear: They have no intentions of budging.

-ABC News' Sarah Kolinovsky

The White House will send 25 million masks to more than 1,300 community health centers, food pantries and soup kitchens to deliver for vulnerable communities, it says.

The masks, which are “high-quality, washable, and consistent with the mask guidance from the CDC,” will be delivered by the Department of Health and Human Services, in partnership with the Department of Defense starting in March through May.

“As a result of these actions, an estimated 12 to 15 million Americans will receive masks. More than 25 million masks total will be distributed,” the administration said in the release.

-ABC News' Molly Nagle

In pre-taped remarks, Biden's new Secretary of State Antony Blinken delivered his first address to the U.N. Human Rights Council since the U.S. moved to rejoin as an observer. Blinken said the U.S. will seek full-time membership for the 2022 term.

In his remarks, Blinken called for reform of the council, including members with anti-Israel bias and members that "undermine" human rights. He even called out a few countries by name, including Russia, Iran, Venezuela and China -- all members. Blinken also noted America’s imperfect human rights record, citing discrimination and violence toward Black, indigenous and Asian Americans.

"I recognize that any pledge to fight for human rights around the world must begin with a pledge to fight for human rights at home," Blinken said. "People of color in the United States deal every day with the consequences of systemic racism and economic injustice."

-ABC News' Conor Finnegan and Chad Murray

Asked by Judiciary Chairman Sen. Dick Durbin whether the Jan. 6 insurrection was a "one-off" domestic terrorism event, Garland said he didn't think it was, citing comments by FBI Director Chris Wray who has outlined the rise in threat of domestic terrorism in recent years.

Garland said he agreed that we are currently facing "a more dangerous period" than the nation faced when he was overseeing the investigation of the Oklahoma City bombing. He said while he has no inside information about the department's investigation into the Capitol rioters, he said "it looks like an extremely aggressive and perfectly appropriate beginning to an investigation" adding it will be his first priority and first briefing upon his return to the department if he's confirmed.

Asked about the Trump Administration's child separations, Garland said the policy was "shameful" and said he would ensure cooperation from Justice Department into the committee's investigation of the policy.

"I can't imagine anything worse than tearing parents from their children and we will provide all the cooperation we possibly can," Garland said.

Garland was asked whether he will let special counsel John Durham finish his investigation, Garland said he had no information on it but has no reason from what he currently knows to believe Durham should be removed. Garland said it will be among his first briefings upon confirmation as Attorney General.

Garland declined to answer a question from Grassley about whether he will commit to defending the death sentence penalties for certain individuals like the Boston marathon bomber, noting they are pending cases.

Grassley also asked whether Garland had any discussions with Biden about the investigation into Hunter Biden.

"I have not. The president made abundantly clear in every public statement before and after my nomination that the decisions about investigations and prosecutions will be left to the justice department," Garland said. "That was the reason that I was willing to take on this job, and so the answer to your question is no."

-ABC News' Alexander Mallin