Merrick Garland, Biden's pick for attorney general, could face tricky political questions during his confirmation hearing before the Senate Judiciary Committee today. In the wake of the Jan. 6 attack on the Capitol, Garland and Democrats are expected to point to Garland's work prosecuting the Oklahoma City bombing as evidence of his ability to investigate and prosecute domestic terrorism.

"If confirmed, I will supervise the prosecution of white supremacists and others who stormed the Capitol on January 6 – a heinous attack that sought to disrupt a cornerstone of our democracy: the peaceful transfer of power to a newly elected government,” Garland will say.

Garland's opening statement also conveys a commitment to equity, saying that upholding the Civil Rights Act remains "urgent" for the Department of Justice. Garland has received ample bipartisan support, ahead of his confirmation hearings before Senate Judiciary Monday and Tuesday, 61 former federal judges and a bipartisan group of more than 150 former Justice Department officials have penned letters in support of Garland's confirmation.

-ABC News' Alexander Mallin and Benjamin Siegel

Energy and Natural Resources Committee Chairman Sen. Joe Manchin, D-W.V., will vote to confirm Rep. Deb Haaland's, D-Ariz., nomination to serve as secretary of the interior, easing concerns that Haaland's appointment could be in jeopardy.

Manchin has been in close focus on this and other nominations this week, as the moderate Democrat has significant ability to jeopardize nominees in the evenly divided Senate.

Manchin has said he will oppose the nomination of Neera Tanden to the Office of Management and Budget and has not committed to a position on Xavier Becerra's nomination to lead the Department of Health and Human Services.

"I believe that every Presidential nominee and every Member of Congress must be committed to a new era of bipartisanship. That is the standard the overwhelming majority of Americans expect and deserve," Manchin said in a statement. "With respect to Representative Haaland and her confirmation hearing, while we do not agree on every issue, she reaffirmed her strong commitment to bipartisanship, addressing the diverse needs of our country and maintaining our nation’s energy independence."

-ABC News' Allison Pecorin