Tonight I’m on Pence and Hutchinson duty. Neither candidate appears to have a great shot at winning the primary — the former vice president is at 4 percent in FiveThirtyEight’s national polling average while the former Arkansas governor hasn’t even garnered 1 percent — but Pence at least has a decent chance of making a debate-night splash. Given the events of Jan. 6, 2021, Pence has the strongest claim to the anti-Trump “lane” of the primary. I wouldn’t be surprised if we saw some real fireworks between him and the GOP candidates who have been quick to jump to Trump’s defense after the bad news he has been hit with over the past year. For his part, Hutchinson will have to pull off a masterclass in persuasion and performance to gain substantial ground. In our poll with Ipsos and The Washington Post, only 6 percent of Republicans said they were even considering voting for him, much less were intending to do so. In a more fluid primary, he’d maybe have a shot at doing something about that. But with Trump as the default and other candidates leading the various anti-Trump lanes, those are really tough numbers to come back from.

–Analysis from G. Elliott Morris_

I’m watching DeSantis tonight. The Florida governor really needs a good performance tonight to reestablish himself as the main alternative to Trump after seeing his national polling average slip from 36 percent in mid-March to just 15 percent today. It will be interesting to see how much he goes after the absent Trump — which has typically been his strategy to this point — versus attacking the other not-Trumps, who are realistically his main competition these days. I’m also curious what bar DeSantis will be measured against. The popular narrative about him is that he’s kind of awkward, so maybe a quote-unquote “presidential” performance will be reassuring to people who are on the fence about him. But our poll with Ipsos and The Washington Post actually found that voters have relatively high expectations when it comes to DeSantis’s debating abilities, so maybe he needs a truly masterful performance in order to move the needle.

–Analysis from Nathaniel Rakich

Attendees seen greeting supporters outside the debate hall in Milwaukee have included former Arizona gubernatorial candidate Kari Lake, Georgia Gov. Brian Kemp and Trump's son Donald Trump Jr.

While Ramaswamy is still "unlikely" to visit the spin room following the debate, his wife, Apoorva Ramaswamy, his communications director and senior adviser Tricia McLaughlin, two other team members and an undisclosed "special guest" will be there on his behalf, according to McLaughlin.

The spin room is the space where campaigns highlight their candidate and attack their opponents after the debate. Many candidates themselves head there after they take the stage.

-ABC News' Kendall Ross

Trump maintains a lead of 28 percentage points over his nearest competitor in South Carolina, according to the latest polls.

Haley and Scott, the two candidates from South Carolina, are both polling higher in South Carolina than they are nationally, according to our polling average. Trump is polling about 7 points lower in South Carolina than in national polls.

Only one pollster, the Manhattan Institute has tested the favorability of Republican candidates in South Carolina since July 1. That survey found Scott and DeSantis had the highest net favorability in the state (+56 and +55 percentage points, respectively), and Trump and Haley close behind (+39 and +33 points, respectively). Pence had a net favorability of +1 point, and Christie was underwater by -36 points.

Economic issues are most important to Republican primary voters in South Carolina, according to a July survey from Fox Business/Beacon Research/Shaw & Co. Research. Fifty-one percent of Republican voters said economic issues would be most important for deciding their vote. Twelve percent each said immigration issues, social issues and foreign policy were most important.

In an August survey by National Public Affairs, 40 percent of South Carolina Republican voters said that Trump wouldn’t lose their support even if he did not show up to the debate. Twelve percent said that they support Trump, but if he didn’t debate they would be open to or definitely supporting someone else, 32 percent said they wouldn’t vote for Trump regardless, 9 percent said they probably wouldn’t watch the debate anyway and 6 percent were unsure.

-Analysis by FiveThirtyEight