In campaign ads and on the trail, the DeSantis campaign has been attacking Haley for recruiting a Chinese fiberglass company to South Carolina while she was governor.

On stage, Haley turned the table on DeSantis.

“Ron, you are the chair of your economic development agency that, as of last week, said Florida is the ideal place for Chinese businesses,” Haley said.

“I abolished that agency that she's talking about,” DeSantis responded.

Haley is pointing to the web page of Select Florida, Florida’s economic development entity. The website talked extensively about business opportunities in China, according to The Messenger. It included a quote from a 2020 report that discussed “positioning Florida as an ideal business destination for Chinese companies.” The references were removed from the website last week.

DeSantis’ office told The Messenger it removed some items from Select Florida's website that were "outdated information on a website for an organization that the governor abolished, so it was updated accordingly."

"Gov. Ron DeSantis signed HB 5 to eliminate Enterprise Florida (EFI), the state’s public-private business development agency. In doing so, DeSantis ended more than 30 years of EFI providing incentives to corporations and – prior to DeSantis’ crackdown – courting Chinese investments," the DeSantis campaign said.

-Analysis by Aaron Sharockman of PolitiFact

The candidates took on TikTok, arguing that the enormously popular if controversial social media app should be banned in the U.S.

Trump "talked tough about TikTok, I heard him do it many times, but when it came down to it, he did not ban them when he could have and should have," Christie said. "In my first week as president, we would ban TikTok."

"I think that China's the top threat we face. They've been very effective at infiltrating different parts of our society," Desantis, the father of three young kids, said. "These kids get these devices, and they have a mind of their own."

Ramaswamy, who has waffled on TikTok usage, targeted Haley's daughter's use of the app, drawing some boos, which he played down as coming from Haley supporters.

"We have to ban any U.S. company actually transferring U.S. data to the Chinese," Ramaswamy added. "Even U.S. companies in Silicon Valley are doing it."

"What we should do is ban TikTok, period," Scott said.

-ABC News' Tal Axelrod

As 538’s Cooper Burton wrote a few months ago, TikTok bans are popular among roughly half of Americans. But one group that is strongly opposed is young Americans, which Republicans have historically struggled with.
-Analysis by Nathaniel Rakich of 538

The two candidates who have perhaps the most acrimonious relationship on stage, Haley and Ramaswamy, have spent a notable amount of the debate sparring with each other.

After Ramaswamy mentioned that Haley's daughter has used TikTok, despite Republican criticism of the Chinese-owned app -- drawing boos from attendees -- Haley admonished him.

"Leave my daughter out of your voice," she said, adding with an eye roll: "You're just scum."

-ABC News' Adam Carlson

Scott, who is trailing the other debate participants in the polls, hopes to make his mark among voters looking for an alternative to Trump, a campaign spokesperson said ahead of the debate.

"At the end of the day, I think what I would expect from Sen. Scott is asking -- who can win?" Matt Gorman, a senior campaign adviser, said on ABC News Live Wednesday. "Is it gonna be a moderate who's coalescing the 'Never Trumpers' like Gov. Haley, or someone who's fallen two-thirds in the polls like Gov. DeSantis, whose only thing that's consistent about his campaign is how much it's underwhelmed?"

Gorman said Scott might look to focus on contrasts among the candidates on policy issues such as abortion. The senator has said that as president he would advocate for a 15-week national ban on abortion.

-ABC News' Meredith Deliso