Late into Biden's remarks, a man was removed from the upper area of the House chamber after shouting out repeatedly.

The man appeared to be yelling about the Marines who were killed in the Abbey Gate bombing at the airport in Kabul, Afghanistan, during the U.S. withdrawal in 2021.

Biden's handling of the American exit was criticized by many at the time, though he has defended ending the protracted and divisive war.

-ABC News' Adam Carlson

Biden departed from his prepared remarks while discussing his border policy after the name Laken Riley was called out, as some in the GOP have blamed the White House's handling of immigration for Riley's death.

The 22-year-old Georgia nursing student was killed last month -- allegedly by a Venezuelan migrant whom officials say was illegally in the U.S.

"Laken Riley! An innocent young woman who was killed by an illegal," Biden said while holding up a Laken Riley pin.

Addressing her parents, he said. "My heart goes out to you having lost children myself."

He said Republicans owe it to Americans to "get this bill done," referring to a Senate agreement to tighten immigration restrictions, which some conservatives say is insufficient to fix the problem.

Biden reiterated his call for Congress to enact stricter gun reform, including banning high-capacity magazines and assault rifles -- while swiping at former President Donald Trump.

"After another school shooting in Iowa [Trump] said we should just 'get over it.' I say we must stop it," Biden said.

"I’m demanding a ban on assault weapons and high-capacity magazines! Pass universal background checks! None of this violates the Second Amendment or vilifies responsible gun owners."

Biden reiterated his calls for several policies at the heart of his domestic agenda, though they are unlikely to become law in this divided Congress.

He urged lawmakers to pass the Equality Act, which would prohibit discrimination against the LGBTQ+ community; the PRO Act, which would protect workers' rights; and the Freedom to Vote Act and the John Lewis Voting Rights Act to bolster voting rights.

"And raise the federal minimum wage because every worker has the right to earn a decent living," he said.

The attendees at Biden's address Thursday were invited because each "personify issues or themes" that he will discuss in his speech, the White House said in a statement.

Biden's guests will shine a spotlight the Israel-Gaza conflict (which has fueled progressive criticism against him) and reproductive freedom battles, gun violence prevention, union protections and more.

Standing behind Biden will be Vice President Kamala Harris on his right and Speaker of the House Mike Johnson on his left. Members of both the Senate and the House of Representatives will be in attendance.

More than a dozen family members of Americans who are thought to still be held hostage in Gaza and Mia Schem, a freed Israeli hostage, will be present at the Capitol.

First lady Jill Biden invited three women working to protect reproductive rights in her box: Kate Cox, Latorya Beasley and Maria Shriver.

Jazmin Cazares, the older sister of a 9-year-old victim of the deadly shooting at Robb Elementary in Uvalde, Texas, will be in attendance, too.

The United Auto Workers union president, Shawn Fain, who recently endorsed Biden, will also be present.