Late into Biden's remarks, a man was removed from the upper area of the House chamber after shouting out repeatedly.

The man appeared to be yelling about the Marines who were killed in the Abbey Gate bombing at the airport in Kabul, Afghanistan, during the U.S. withdrawal in 2021.

Biden's handling of the American exit was criticized by many at the time, though he has defended ending the protracted and divisive war.

-ABC News' Adam Carlson

Biden departed from his prepared remarks while discussing his border policy after the name Laken Riley was called out, as some in the GOP have blamed the White House's handling of immigration for Riley's death.

The 22-year-old Georgia nursing student was killed last month -- allegedly by a Venezuelan migrant whom officials say was illegally in the U.S.

"Laken Riley! An innocent young woman who was killed by an illegal," Biden said while holding up a Laken Riley pin.

Addressing her parents, he said. "My heart goes out to you having lost children myself."

He said Republicans owe it to Americans to "get this bill done," referring to a Senate agreement to tighten immigration restrictions, which some conservatives say is insufficient to fix the problem.

Biden reiterated his call for Congress to enact stricter gun reform, including banning high-capacity magazines and assault rifles -- while swiping at former President Donald Trump.

"After another school shooting in Iowa [Trump] said we should just 'get over it.' I say we must stop it," Biden said.

"I’m demanding a ban on assault weapons and high-capacity magazines! Pass universal background checks! None of this violates the Second Amendment or vilifies responsible gun owners."

Biden reiterated his calls for several policies at the heart of his domestic agenda, though they are unlikely to become law in this divided Congress.

He urged lawmakers to pass the Equality Act, which would prohibit discrimination against the LGBTQ+ community; the PRO Act, which would protect workers' rights; and the Freedom to Vote Act and the John Lewis Voting Rights Act to bolster voting rights.

"And raise the federal minimum wage because every worker has the right to earn a decent living," he said.

Republicans plan to keep an empty seat in memoriam of Laken Riley, a 22-year-old nursing student who was killed on the University of Georgia's Athens campus last month.

Rep. Mike Collins, R-Ga., said he invited Riley's parents to be guests at the State of the Union though "they have chosen to stay home as they grieve the loss of their daughter."

Biden's address comes hours after the House passed the Laken Riley Act, which would require detention of any unauthorized migrant who commits burglary or theft.

The suspect charged in Riley's killing, Jose Antonio Ibarra, unlawfully entered the U.S. near El Paso, Texas, in September 2022 and was paroled and released for further processing, U.S. Immigration and Customs Enforcement said following his arrest in Georgia.

ICE said that Ibarra was subsequently arrested by New York City police in 2023 and released before federal officials could ask for his detention. The NYPD has said there is no arrest on file.

The Laken Riley Act passed the House 251-170, with 37 Democrats voting for it. Some opposing it believe Republicans are using Riley's death for their own political gain to place blame on the Biden administration's border policies as polling shows immigration is a top issue for some voters.