The Note: Top Political Stories of the Day

Trump Calls Washington Leadership 'Losers' and 'Babies.’ After a lighthearted evening in which he traded barbs with Hillary Clinton at a charity dinner, Donald Trump was back on the attack today, calling out Washington leadership and condemning the Obamas for campaigning for Clinton. “We have a bunch of babies running our country, folks,” said Trump at a campaign rally in Fletcher, North Carolina. “We have a bunch of losers, they’re losers, they’re babies.” ABC’s ADAM KELSEY and CANDACE SMITH have more: http://abcn.ws/2dvAayJ

The Longshot Path for Trump to Win 270 Electoral Votes. Donald Trump’s path to the White House is fading fast. With national polls showing Hillary Clinton growing her lead and Trump losing his grip on traditionally red states, Clinton looks likely to prevail on Election Day. Clinton can afford to lose classic battlegrounds like Ohio and Florida as long as she holds onto light blue states like Pennsylvania and Colorado. An ABC News analysis out today estimates Clinton is already poised to win at least 300 electoral votes –- even if Donald Trump wins every toss-up state. ABC’s RYAN STRUYK has more: http://abcn.ws/2eBTQTK

TALES FROM THE TRAIL

ABC’s INES DE LA CUETARA: Mike Pence this afternoon spoke to a group of about 100 students at the Nashua Christian Academy in New Hampshire. Pence mostly encouraged students to follow their dreams, work hard, and have faith. He said the two heroes of his youth were MLK and JFK, and that both inspired him to work in public service. Funny moment when Pence said he figured if JFK had done it, he could do it too. “And I was right!” he exclaimed. Pence paused but the crowd remained silent, causing Pence to echo Jeb Bush’s “please clap” moment by asking, “Can I get a round of applause about that?"

AD ROUNDUP with ABC’s SHUSHANNAH WALSHE

New Clinton TV Ad features Khizr Khan. The Clinton campaign released a new TV ad today featuring Khizr Khan, who was outspoken against Trump at the Democratic National Convention. In a moving and powerful one minute spot, Khan recounts the death of his son, Muslim American and Army Cpt. Humayun, and says: "I want to ask Mr. Trump, would my son have a place in your America?” The ad will air as part of an already existing ad buy in Florida, Iowa, Nevada, New Hampshire, North Carolina, Ohio and Pennsylvania. WATCH: http://bit.ly/2erfLMH

QUOTE OF THE DAY:

“We will shock the world. This is going to be Brexit plus and a lot of people know it. They say, we can’t poll this thing.” -- Donald Trump

HAPPENING TONIGHT (all times Eastern):

--6:30 PM - Mike Pence participates in a town hall in Exeter, New Hampshire.

--7:30 PM - Donald Trump heads to Newtown, Pennsylvania for a campaign rally.

--10 PM - Donald Trump will be interviewed on Fox News.

WHAT TO WATCH FOR THIS WEEKEND:

This Week on ‘This Week’: The Powerhouse Roundtable debates the week in politics, with ABC News political analyst Matthew Dowd, Republican strategist and CNBC contributor Sara Fagen, National Review senior editor Jonah Goldberg, Democratic strategist Jamal Simmons, and editor and publisher of The Nation Katrina vanden Heuvel.

WHO’S TWEETING?

@karentravers: Clinton has a deep bench helping her on the trail. Donald Trump, not so much. Our piece on impact of surrogates http://abcn.ws/2erBILV

@ryanstruyk: NEW: @ABC has changed ARIZONA and UTAH to TOSSUP in presidential race. Clinton estimated at 300+ electoral votes. http://abcn.ws/1U7c52f

@mviser: Jan Brewer doesn't think there will be a wave of Hispanic voters. "Nah," she told me. "They don't get out and vote." http://www.bostonglobe.com/news/politics/2016/10/21/hillary-clinton-looks-expand-political-map/MexXdjQtXdjB5l8B6SeFIM/story.html

@kenvogel: Clinton's team worried about her over-exuberant laughter. Podesta: "Laughing too hard is her authentic weirdness." https://wikileaks.org/podesta-emails/emailid/24257 …

@joshrogin: Curt Schilling asks @jaketapper how Jews can support Democrats. Tapper: "I don't speak for Jews." @TheLeadCNN