Republican Presidential Debate: The Best Zingers From The Second Republican Debate

— -- Candidates rolled their eyes and threw plenty of punches on the GOP debate stage tonight.

The second Republican debate was filled with memorable lines and zingers ranging from quips to personal attacks by candidates -- many from frontrunner Donald Trump and Carly Fiorina.

“First of all, Rand Paul shouldn't even be on this stage,” Trump said. “He's number 11 and has 1 percent in the polls and how he got up here there is far too many people anyway --Rand Paul shouldn't even be on this stage!”

Paul shot back, calling Trump "sophomoric."

“Do we want someone like that to be negotiating with Iran?," he asked. "I think really there is a sophomoric quality that is entertaining about Mr. Trump...Would we not all be worried to have someone like that in charge of the nuclear arsenal?”

Trump shot back with another zinger.

“I never attacked him on his looks and believe me, there is plenty of subject matter there," he said. "That I can tell you."

Later, Trump went on the offensive against former New York Gov. George Pataki as a “failed governor” who “wouldn’t be elected dogcatcher.”

Trump and Jeb Bush also squared off about whether Trump said he wanted to build a casino in Bush’s state of Florida. The bickering ended with Trump bringing up one of his favorite zingers against Bush: “More energy tonight--I love that!”

Fiorina also took on Trump and his comments about her face in a recent Rolling Stone interview.

"Women all over this country heard very clearly what Mr. Trump said," Fiorina responded to some of the loudest applause of the night.

Fiorina and Trump weren't the only candidates to get a strong response from the audience. Laughter erupted after the famous neurosurgeon Dr. Ben Carson turned one of Trump's criticisms of him around. Carson called Trump an "an O.K. doctor" after he explained his position on vaccines.