How the Secret Service, Vatican Security Are Teaming Up to Protect Pope Francis During US Visit

Pope Francis' trip presents a "tremendous challenge."

Secret Service agents in charge of the pope’s security detail met with the head of Vatican security, both in Rome and in the United States to discuss details of the trip.

“I went out to Rome to see firsthand how their detail works, protecting the pope and what he likes to do and how he travels within the crowds,” said Clancy in an interview with ABC News' Senior Justice Correspondent Pierre Thomas at the Secret Service Rowley Training Center.

The pontiff's visit, which coincides with the U.N. General Assembly meeting, presents a “tremendous challenge,” Clancy said.

“He loves to be out with the people,” he said.

Francis has become known for mingling with and shaking hands of people in the crowds that amass for his public appearances.

The Secret Service has been watching closely as the pope travels throughout South America to see how the interacts with crowds.

“Each protectee is different, whether it's presidents or certainly the pope and we have to adapt to some of the things that they want to accomplish,” Clancy said.

“We expect large crowds for the people and we're prepared for that,” he said.

ABC News' Phoebe Natanson contributed to this report.