In the wake of the Derek Chauvin guilty verdict, several celebrities and athletes took to social media to react.

NBA star LeBron James summed it up in one word: "Accountability."

U.S. Open champ Naomi Osaka, who wore masks with the names of victims of racial injustice and police brutality during the tournament, including Floyd's, said she was "hit with sadness because we are celebrating something that is clear as day."

Oprah Winfrey tweeted a photo of a young Floyd, saying she was "relieved" and "cried tears of joy as each verdict was read."

TV producer Shonda Rhimes said the verdict "does not bring back Mr Floyd. But justice is truth."

Whoopi Goldberg had a similar sentiment. "No one wins," she tweeted. "George Floyd is still gone."

"Black-ish" star Tracee Ellis Ross said she is "weeping with grief and relief for George’s family, his loved ones, and this country."

Model Bella Hadid shared a photo of Floyd with his daughter, saying, "Thank God for justice and accountability today."

Actor George Takei, paraphrasing Martin Luther King Jr., tweeted that "the moral arc of the universe has finally bent toward" justice.

Singer Barbra Streisand thanked the jury and the high schooler, Darnella Frazier, who filmed the viral video of the "horrible act."

Minneapolis Mayor Jacob Frey described a city "gripped in grief" in the 11 months since George Floyd died while in police custody, as many residents took to the streets Tuesday to celebrate the verdict in the Derek Chauvin trial.

"This is a good day in Minneapolis," Frey said during a press briefing a few hours after the verdict was announced. "But let me be exceedingly clear: This is day one."

"Justice has been rendered in this case, but we still have a long way to go to achieve true justice in our city and in our country," he said, noting that the city is "piloting new ways of policing" in the wake of George Floyd's death.

The mayor said he was "relieved" by the verdict, and thanked the jurors and witnesses who testified.

"We all wanted to see justice, we all wanted to make sure that, again, this was day one of the necessary change that we needed to see," Frey said. "And I think we all were nervous that what has happened on so many occasions, through our judicial system, where we wouldn't see that justice would happen." 

The verdict comes as the city is also reeling from the fatal police shooting of Daunte Wright while being detained by police last week in Brooklyn Center, a Minneapolis suburb. The shooting sparked widespread protests.

A curfew has not been issued for Tuesday night, "although that certainly remains an option on the table if necessary," Frey said. "That is not the desired approach, but it is an option that will be available."

Department of Homeland Security Secretary Alejandro Mayorkas weighed in on the conviction of Derek Chauvin on Twitter, Tuesday night.

Mayorkas said the verdict was "a step toward accountability," but said "it will not erase the pain felt by the Floyd family and Black Americans."

"I speak for myself and the entire Department of Homeland Security in reaffirming our commitment to do our part to end injustice as we work to make our country a safer and more equitable Nation for all," he tweeted.

Maorkas added that DHS is in contact with state and local agencies to ensure that citizens peacefully make their voices heard.

-ABC News' Luke Barr

President Joe Biden and Vice President Kamala Harris reacted to the verdict in the Derek Chauvin trial in an address from the White House.

Biden called the guilty verdict a "giant step forward in the march toward justice in America" and commended the witnesses who testified, including police officers.

"Most men and women who wear the badge serve their communities honorably. Those few who failed to meet that standard must be held accountable, and they were today. One was," Biden said. "No one should be above the law. And today's verdict sends that message."

"But it's not enough," he continued. "We can't stop here. In order to deliver a real change in reform, we can and we must do more to reduce the likelihood that tragedy like this will ever happen to occur again."

Harris called the verdict a step forward in law enforcement reform.

"A measure of justice isn’t the same as equal justice," she said. "We still have work to do."

Harris said she and Biden will continue to urge the Senate to pass the George Floyd Justice in Policing Act.

"Black men are fathers and brothers and sons and uncles and grandfathers and friends and neighbors," she said. "Their lives must be valued in our education system, in our health care system, in our housing system, in our economic system, in our criminal justice system, in our nation -- full stop."