Columbia University President Minouche Shafik said that tensions on campus had "rose to new heights" when a group of protesters broke into Hamilton Hall and barricaded themselves. Shafik said it pushed the university "to the brink," according to a letter sent to the Columbia University community Wednesday.

"I know I speak for many members of our community in saying that this turn of events has filled me with deep sadness. I am sorry we reached this point," Shafik said.

The NYPD said it arrested 119 people at Columbia Tuesday night, but it has not yet revealed how many of those arrested are students.

"The University offered to consider new proposals on divestment and shareholder activism, to review access to our dual degree programs and global centers, to reaffirm our commitment to free speech, and to launch educational and health programs in Gaza and the West Bank. Some other universities have achieved agreement on similar proposals. Our efforts to find a solution went into Tuesday evening, but regrettably, we were unable to come to resolution," Shafik said.

Negotiations broke down between the university and members of the encampment after Columbia refused to divest from companies linked to Israel and the war in Gaza.

The University of California, Los Angeles announced that it will cancel all Wednesday classes due to the "distress caused by the violence that took place on Royce Quad" overnight, according to a statement from the university.

The hospital and health system, the Luskin Conference Center and PreK through 12 schools will remain open.

"We have law enforcement presence stationed throughout campus to help promote safety. Student Affairs will have essential staff on campus to support our students who have been impacted by this tragedy," UCLA said in a statement.

At least 12 people have been arrested at the University of Wisconsin-Madison as campus police moved to disperse an encampment of protesters. About 100 to 200 people had arrived for a demonstration Monday and began putting up tents.

The University of Wisconsin said several people resisted arrest, but it is not yet clear how many of the arrested are affiliated with the university.

Several tents have been taken down and dissembled.

"Tents and camping are not allowed on any university property under Chapter 18 of the Wisconsin Administrative Code, which defines the types of activities permitted on campus, information which was shared to all members of the campus community on Friday," the university said in a statement.

The mayor said those who occupied Hamilton Hall were led by people unaffiliated with Columbia University.

Those protesters made a change to more aggressive tactics and represented an "elevated concern," Rebecca Weiner, the NYPD deputy commissioner of intelligence and counterterrorism, said Wednesday.

"The situation had deteriorated to the point where the safety of students, staff and the public was at risk," Police Commissioner Edward Caban said.

There were 282 arrests on a range of mainly minor offenses -- 173 at City College and 119 at Columbia.

"It was a tough decision," Adams said, of the university authorizing the NYPD to move onto campus. "The action had to end and we brought it to a peaceful conclusion."

-ABC News' Aaron Katersky

After police and protesters clashed on the campus of the University of Texas at Austin following a dispersal order, leading to some arrests on Monday, the school issued a statement, saying it "took swift action to preserve a safe, conducive learning environment for our 53,000 students as they prepare for final exams."

"UT Austin requested backup assistance from the Texas Department of Public Safety to protect the safety of the campus community and enforce our Institutional Rules, such as the rule that prohibits encampments on campus. Because of the encampments and other violations of the University’s Institutional Rules related to protests, protestors were told repeatedly to disperse. When they refused to disperse, some arrests were made for trespassing. Others were arrested for disorderly conduct," the university's statement read.

UTA said protests since the start of the Israel-Hamas war have happened "largely without incident."

"The University strongly supports the free speech and assembly rights of our community and we want students and others on campus to know that protests on campus are fully permissible, provided that they do not violate Institutional Rules or threaten the safety of our campus community," the statement concluded.

-ABC News' Marilyn Heck