Hurricane Ian updates: Florida death toll climbs
Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
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5,000 Florida Guardsmen activated and prepping for Hurricane Ian
Florida Gov. Ron DeSantis has activated 5,000 Florida National Guardsmen to armories across the state in preparation for Hurricane Ian, which is forecast to hit the state on Wednesday.
Roughly 2,000 National Guard members from neighboring states such as Tennessee are also being activated to assist, the Florida National Guard said in a statement Tuesday.
"The Florida National Guard is well-equipped, with assets including high-wheeled vehicles, helicopters, boats, generators and more," the statement said.
The U.S. Navy has authorized non-essential personnel in various Florida counties to evacuate.
-ABC News’ Matt Seyler
Landfall forecast for Wednesday afternoon or evening
Hurricane Ian, barreling north toward Florida with 120 mph winds, is now located about 230 miles away from Sarasota.
Ian is expected to make landfall in Florida on Wednesday afternoon or early evening.
Ian's outer bands are already hitting South Florida, bringing a threat of heavy downpours, strong wind gusts, frequent lightning and even tornadoes. A tornado watch is in effect for South Florida until 5 a.m. Wednesday.
-ABC News’ Dan Peck
Walt Disney World, Universal Orlando to close
Walt Disney World and Universal Orlando will close Wednesday and Thursday due to the storm.
Coastal Georgia, South Carolina under tropical storm watches
As Ian moves north over Florida, tropical storm force winds will reach coastal Georgia and South Carolina.
Tropical storm watches have been issued for Savannah and near Charleston.
Georgia Gov. Brian Kemp has issued a state of emergency.
Biden calls Florida damage 'among worst in nation's history'
President Joe Biden spoke from the White House Friday afternoon about Hurricane Ian's wrath, describing the devastation in Florida as well as warning residents of South Carolina to be prepared for another landfall.
"We're just beginning to see the scale of that destruction," Biden said of the damage in Florida. "It is likely to rank among the worst in the nation's history. You have all seen on television, homes and property wiped out. It is going to take months, years to rebuild."
He added, "I just want the people of Florida to know we see what you are going through and we are with you. And we are going to do everything we can for you."
Biden said the U.S. Coast Guard has mobilized 16 helicopters, 18 rescue boats and six fixed-wing planes to help in search and rescue in Florida. More than 100 people have been rescued by the Coast Guard, Biden said. Hundreds more have been rescued by volunteers.
"The federal government will cover every cost, 100% of the cost, to clear the massive debris left in the wake of the hurricane and these counties," the president said. "It all needs to be cleared out for communities to begin the hard work of trying to get back on their feet."