Hurricane Ian updates: Florida death toll climbs
Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
Latest headlines:
Ian’s eyewall moving on shore
Hurricane Ian’s eyewall is moving on shore.
The powerful Category 4 storm is set to bring catastrophic storm surge, winds and flooding.
Sanibel Island has reported sustained winds of 58 mph with a wind gust reaching 75 mph.
Over 2,000 flights canceled
The airports in Orlando, Miami, Tampa and Fort Lauderdale are leading the world in flight cancellations Wednesday morning.
Over 2,000 flights have been canceled within, into, or out of the United States on Wednesday.
Another 1,600 flights are already cancelled for Thursday.
The Tampa International Airport will remain closed through Thursday.
-ABC News’ Ahmad Hemingway and Sam Sweeney
Hurricane-force winds approaching Florida coast
Hurricane-force winds are approaching the coast of Florida near Sanibel Island, which is 23 miles from Fort Myers.
FEMA Administrator Deanne Criswell stressed Wednesday the danger of water as Hurricane Ian approaches.
She urged Floridians to never drive through floodwaters, noting a car can be carried away in just a few inches of water.
“From coastal storm surge to inland flooding, the majority of the state of Florida is in Ian’s crosshairs,” she said.
18 feet of storm surge possible
Up to 18 feet of dangerous storm surge is forecast along Florida’s Southwest coast, including Englewood, Bonita Beach and Charlotte Harbor.
FEMA Administrator Deanne Criswell warned Tuesday that her biggest concern with Ian was storm surge.
"In 2018, when Hurricane Michael impacted the Florida Panhandle, there were five recorded fatalities as a result of storm surge,” she noted.
Biden calls Florida damage 'among worst in nation's history'
President Joe Biden spoke from the White House Friday afternoon about Hurricane Ian's wrath, describing the devastation in Florida as well as warning residents of South Carolina to be prepared for another landfall.
"We're just beginning to see the scale of that destruction," Biden said of the damage in Florida. "It is likely to rank among the worst in the nation's history. You have all seen on television, homes and property wiped out. It is going to take months, years to rebuild."
He added, "I just want the people of Florida to know we see what you are going through and we are with you. And we are going to do everything we can for you."
Biden said the U.S. Coast Guard has mobilized 16 helicopters, 18 rescue boats and six fixed-wing planes to help in search and rescue in Florida. More than 100 people have been rescued by the Coast Guard, Biden said. Hundreds more have been rescued by volunteers.
"The federal government will cover every cost, 100% of the cost, to clear the massive debris left in the wake of the hurricane and these counties," the president said. "It all needs to be cleared out for communities to begin the hard work of trying to get back on their feet."