Ian, now a Category 3 hurricane with 120 mph winds, has strengthened on Tuesday and is forecast to strengthen even more into the night.

The latest track shows Ian making landfall on Wednesday, striking the west coast of Florida between Tampa and Fort Myers, bringing flooding and damaging winds.

Hurricane warnings are in effect from Tampa to Fort Myers and storm surge warnings are in effect for a large portion of Florida’s west coast.

There is also a risk for tornadoes in Florida Tuesday and Wednesday.

Federal Emergency Management Agency Administrator Deanne Criswell warned Tuesday, "Floridians are going to experience the impacts from the storm for a very long time."

"Our biggest concern as we wait for this storm to make landfall is storm surge," Criswell said. "In 2018, when Hurricane Michael impacted the Florida Panhandle, there were five recorded fatalities as a result of storm surge. So therefore, if people are told to evacuate by their local officials, please listen to them. The decision you choose to make may mean the difference between life and death."

President Joe Biden on Tuesday urged residents to "evacuate when ordered."

Biden said he spoke to the mayors of Tampa, St. Petersburg and Clearwater Tuesday morning and told them to "contact me directly" for "whatever they need."

Criswell said a search and rescue coordination group has been activated, including members from FEMA's urban search and rescue teams, the Coast Guard, the Department of Defense and the Department of the Interior.

The Red Cross has established 29 shelters and is prepared to open 60 more shelters if needed, she said.

Criswell stressed, "To those who may be watching at home, get ready and do not underestimate the potential that the storm can bring."

The Orlando International Airport said operations will stop at 10:30 a.m. Wednesday.

The St. Pete-Clearwater International Airport is closing at 1 p.m. Tuesday while Tampa International Airport is suspending flights at 5 p.m. Tuesday.

The Sarasota Bradenton International Airport is closing at 8 p.m. Tuesday while the Melbourne Orlando International Airport will stop flights at 2 p.m. Wednesday.

Hurricane Ian’s track is moving south, with landfall forecast for late afternoon Wednesday between Tampa and Fort Myers as a Category 3 storm.

The storm surge forecast for Tampa Bay has dropped from 10 feet to 8 feet. But now the predicted storm surge for Fort Myers has increased and could be as high as 12 feet.

Despite water receding in Fort Myers following Hurricane Ian's destructive path across Florida, 80% of the city is still without power, while 70% is without water, Mayor Kevin Anderson told ABC News Live Prime.

Anderson said the most important thing is to get electricity and water back up and running for residents, especially since it's still hot and humid in the area and people need air conditioning and water.

"Tomorrow, we're expecting the delivery of the pods with the water and food and ice and we'll be setting up delivery stations," he said. "Again, the problem is it's very, very difficult to live here without air conditioning."

Fort Myers has performed about 200 rescues and counting, according to the mayor.

"The crews were out and they're probably still out there working now, getting the roads cleared and getting the roads where they're traversable so that emergency vehicles can respond," Anderson said.