Five-thousand members of the Florida National Guard have been activated to help during Hurricane Ian. Another 2,000 guardsmen from Tennessee, Georgia and North Carolina are also coming to help, Florida Gov. Ron DeSantis said.

Nearly 300 ambulances and support vehicles are being deployed to areas bracing for Ian’s landfall, DeSantis said.

-ABC News’ Alex Faul

In Tampa, where residents are bracing for 10 feet of dangerous storm surge, the Tampa International Airport may shut down parts of its airfield and facilities over the next day or two, airport officials announced.

The airport is in an evacuation zone, but because it’s critical infrastructure, it’s “exempt from the storm evacuation order and will stay open until a closure is necessary,” airport officials said in a statement.

It’s been 101 years since Tampa last had a direct hit from a major hurricane.

Hillsborough County Public Schools in Tampa will be closed Monday through Thursday due to the storm. Instead, some schools will operate as storm shelters, the district said.

In Sarasota County, schools will be closed on Tuesday.

NASA said it will roll the Artemis I rocket off the launch pad and back to the vehicle assembly building on Monday night due to the storm.

“Managers met Monday morning and made the decision based on the latest weather predictions associated with Hurricane Ian, after additional data gathered overnight did not show improving expected conditions for the Kennedy Space Center area,” NASA said in a statement. “The decision allows time for employees to address the needs of their families and protect the integrated rocket and spacecraft system.”

The U.S. Department of Health and Human Services has declared a public health emergency for the state of Florida.

HHS Secretary Xavier Becerra made the declaration Monday to address the possible health impacts for Florida residents once Hurricane Ian nears the state.

"We will do all we can to assist Florida officials with responding to the health impacts of Hurricane Ian," Becerra said in a statement. "We are working closely with state, local, and tribal health authorities, as well as our federal partners, and stand ready to provide additional public health and medical support."

HHS has pre-positioned two 15-person health and medical task force teams from its National Disaster Medical System, as well as a 13-person incident management team and two pharmacists to assist with the response in Florida.

"These teams are highly trained and ready to respond if, when, and where they may be needed following the storm," HHS Assistant Secretary for Preparedness and Response Dawn O’Connell said.

Florida Gov. Ron DeSantis declared a state of emergency on Saturday. That declaration was approved by President Joe Biden on Sunday.