Hurricane Ian updates: Florida death toll climbs
Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
Latest headlines:
As flooding begins Charleston police urge 'only essential travel'
Hours before Hurricane Ian is expected to make landfall in South Carolina, Charleston police are urging "only essential travel" and announcing road closures.
"We are experiencing flooding in many of our usual locations and implementing road closure procedures. We expect additional closures throughout the day," police said in a tweet.
Flash flood warning issued for Charleston, South Carolina
The National Weather Service has issued a flash flood warning for the Charleston metro area until noon on Friday.
The NWS says that heavy rain and tide will continue to increase and cause life-threatening conditions and flash flooding.
-ABC News' Max Golembo
Florida governor set to hold early morning press conference on Hurricane Ian
Florida Governor Ron DeSantis will hold his next press conference at 8:45 a.m. ET, according to a media advisory provided by his office.
DeSantis will be joined by FEMA administrator Deanne Criswell.
-ABC News' Ahmad Hemingway
Biden declares state of emergency in South Carolina
President Joe Biden has declared a state of emergency in South Carolina, the White House announced late Thursday night, as Hurricane Ian takes aim at the state.
-ABC News' Lauren Minore
Ian weakens slightly but will regain strength overnight
Tropical Storm Ian has weakened slightly, but it is expected to not only strengthen but rapidly intensify overnight as it travels over warm waters in the Caribbean.
As of 5 p.m. ET, the storm system had maximum sustained winds of 45 mph and was moving west-northwest at 12 mph, with the center located about 220 miles away from Grand Cayman.
Dry air ahead of the storm has delayed the strengthening trend so far. But the rapid intensification is expected to occur Monday into Tuesday as the system continues across the northwestern Caribbean and closes in on western Cuba.
Over the next 24 hours, the outer bands will impact Jamaica and the Cayman Islands, bringing rounds of heavy rain, possible flash flooding and storm surge. Later Monday and into Monday night, Ian will be closing in on western Cuba and will likely bring significant wind and storm surge impacts to the region.
A hurricane warning is in effect for Grand Cayman and portions of western Cuba. A tropical storm watch has been issued for portions of western Cuba, as well as the lower Florida Keys, including Key West.
As of 5 p.m., the forecast track was nudged slightly eastward. Overall, the forecast guidance variability and uncertainty will remain high, and the track for where the storm will be from the middle to the end of the week will continue to shift over the next 24 to 48 hours.
-ABC News' Dan Peck