Hurricane Ian updates: Florida death toll climbs
Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
Latest headlines:
Ian’s eyewall moving on shore
Hurricane Ian’s eyewall is moving on shore.
The powerful Category 4 storm is set to bring catastrophic storm surge, winds and flooding.
Sanibel Island has reported sustained winds of 58 mph with a wind gust reaching 75 mph.
Over 2,000 flights canceled
The airports in Orlando, Miami, Tampa and Fort Lauderdale are leading the world in flight cancellations Wednesday morning.
Over 2,000 flights have been canceled within, into, or out of the United States on Wednesday.
Another 1,600 flights are already cancelled for Thursday.
The Tampa International Airport will remain closed through Thursday.
-ABC News’ Ahmad Hemingway and Sam Sweeney
Hurricane-force winds approaching Florida coast
Hurricane-force winds are approaching the coast of Florida near Sanibel Island, which is 23 miles from Fort Myers.
FEMA Administrator Deanne Criswell stressed Wednesday the danger of water as Hurricane Ian approaches.
She urged Floridians to never drive through floodwaters, noting a car can be carried away in just a few inches of water.
“From coastal storm surge to inland flooding, the majority of the state of Florida is in Ian’s crosshairs,” she said.
18 feet of storm surge possible
Up to 18 feet of dangerous storm surge is forecast along Florida’s Southwest coast, including Englewood, Bonita Beach and Charlotte Harbor.
FEMA Administrator Deanne Criswell warned Tuesday that her biggest concern with Ian was storm surge.
"In 2018, when Hurricane Michael impacted the Florida Panhandle, there were five recorded fatalities as a result of storm surge,” she noted.
Ian weakens slightly but will regain strength overnight
Tropical Storm Ian has weakened slightly, but it is expected to not only strengthen but rapidly intensify overnight as it travels over warm waters in the Caribbean.
As of 5 p.m. ET, the storm system had maximum sustained winds of 45 mph and was moving west-northwest at 12 mph, with the center located about 220 miles away from Grand Cayman.
Dry air ahead of the storm has delayed the strengthening trend so far. But the rapid intensification is expected to occur Monday into Tuesday as the system continues across the northwestern Caribbean and closes in on western Cuba.
Over the next 24 hours, the outer bands will impact Jamaica and the Cayman Islands, bringing rounds of heavy rain, possible flash flooding and storm surge. Later Monday and into Monday night, Ian will be closing in on western Cuba and will likely bring significant wind and storm surge impacts to the region.
A hurricane warning is in effect for Grand Cayman and portions of western Cuba. A tropical storm watch has been issued for portions of western Cuba, as well as the lower Florida Keys, including Key West.
As of 5 p.m., the forecast track was nudged slightly eastward. Overall, the forecast guidance variability and uncertainty will remain high, and the track for where the storm will be from the middle to the end of the week will continue to shift over the next 24 to 48 hours.
-ABC News' Dan Peck