Hurricane Ian updates: Florida death toll climbs
Lee County, which encompasses Fort Myers, accounts for most of the fatalities.
The remnants of Ian are charging up the East Coast on Saturday after making landfall as a Category 1 hurricane in South Carolina on Friday afternoon.
The monster storm made its first U.S. landfall on Wednesday on Florida's west coast as a powerful Category 4 hurricane, shredding homes with ferocious winds topping 150 mph. Florida's death toll has climbed to at least 81, according to information from local officials.
Latest headlines:
Ian’s eyewall moving on shore
Hurricane Ian’s eyewall is moving on shore.
The powerful Category 4 storm is set to bring catastrophic storm surge, winds and flooding.
Sanibel Island has reported sustained winds of 58 mph with a wind gust reaching 75 mph.
Over 2,000 flights canceled
The airports in Orlando, Miami, Tampa and Fort Lauderdale are leading the world in flight cancellations Wednesday morning.
Over 2,000 flights have been canceled within, into, or out of the United States on Wednesday.
Another 1,600 flights are already cancelled for Thursday.
The Tampa International Airport will remain closed through Thursday.
-ABC News’ Ahmad Hemingway and Sam Sweeney
Hurricane-force winds approaching Florida coast
Hurricane-force winds are approaching the coast of Florida near Sanibel Island, which is 23 miles from Fort Myers.
FEMA Administrator Deanne Criswell stressed Wednesday the danger of water as Hurricane Ian approaches.
She urged Floridians to never drive through floodwaters, noting a car can be carried away in just a few inches of water.
“From coastal storm surge to inland flooding, the majority of the state of Florida is in Ian’s crosshairs,” she said.
18 feet of storm surge possible
Up to 18 feet of dangerous storm surge is forecast along Florida’s Southwest coast, including Englewood, Bonita Beach and Charlotte Harbor.
FEMA Administrator Deanne Criswell warned Tuesday that her biggest concern with Ian was storm surge.
"In 2018, when Hurricane Michael impacted the Florida Panhandle, there were five recorded fatalities as a result of storm surge,” she noted.
Tropical Storm Ian will rapidly intensify Sunday, forecasts show
Ian remains a tropical storm with winds of 50 mph, but the storm system is expected to rapidly intensify on Sunday as it moves over warm waters in the Caribbean Sea, according to the National Hurricane Center.
The seawater currently carries very favorable conditions for strengthening over the coming days, with temperatures between 85 and 90 degrees Fahrenheit -- the perfect temperatures for fueling a powerful storm as it stays over open water.
Ian is expected to strengthen to a hurricane by Sunday night and into a major hurricane later Monday night as it passes by Cuba.
The NHC currently forecasts Ian to strengthen into a major Category 4 hurricane on Tuesday in the Gulf of Mexico as it heads toward Florida.
Ian is expected to make landfall on the west coast or the panhandle of Florida on Wednesday or Thursday.
Some weakening could occur before the storm system makes landfall, possibly dipping below major hurricane status before impacting coastal communities.
A hurricane warning is currently in effect for the western portion of Cuba, where flooding rains and major storm surge are forecast.
-ABC News' Riley Winch