House Speaker Nancy Pelosi condemned Republicans in response to the Supreme Court decision, saying in a statement, "Because of Donald Trump, Mitch McConnell, the Republican Party and their supermajority on the Supreme Court, American women today have less freedom than their mothers."

Pelosi further said there would be more restrictions on reproductive health care, claiming, "Republicans want to arrest doctors for offering reproductive care and women for terminating a pregnancy. GOP extremists are even threatening to criminalize contraception, as well as in-vitro fertilization and post-miscarriage care."

She called the ruling "outrageous and heart-wrenching."

Anti-abortion group March for Life praised the Supreme Court's decision to overturn Roe v. Wade, overturning federal protections for abortion.

"Today, the ability to determine whether and when to limit abortion was returned to the American people who have every right to enact laws like Mississippi's which protect mothers and unborn babies after 15 weeks," March for Life said in a statement.

The group called Roe v. Wade an "unpopular and extreme" abortion policy that had been imposed on the U.S. Polling shows 58% of Americans say abortion should be legal in all or most cases.

"We are so grateful to the countless pro-life people of goodwill who contributed and sacrificed to make today possible – including the millions of those who have marched for life over the years - and we recognize that this is just the beginning of our work to advance policies that protect life. We will continue to march until abortion is unthinkable because equality begins in the womb," March for Life said.

Senate Majority Leader Chuck Schumer, in a statement following the Dobbs decision, called Friday one of the "darkest days our country has ever seen" and directly blamed "MAGA Republicans" for the decision.

"These justices were intentionally appointed by Republicans to overturn Roe v. Wade and every Republican Senator knew this would happen if they voted to confirm these radical justices," Schumer said in a statement. "These MAGA Republicans are all complicit in today’s decision and all of its consequences for women and families in this country."

He pointed to the upcoming midterm elections and called on voters to support Democratic causes.

"Today's decision makes crystal clear the contrast as we approach the November elections: elect more MAGA Republicans if you want nationwide abortion bans, the jailing of women and doctors and no exemptions for rape or incest. Or, elect more pro-choice Democrats to save Roe and protect a woman’s right to make their own decisions about their body, not politicians."

-ABC News' Allison Pecorin

Former Vice President Mike Pence praised the SCOTUS decision Friday overturning Roe v. Wade.

“Today, Life Won," Pence said in a statement. "By overturning Roe v. Wade, the Supreme Court of the United States has given the American people a new beginning for life, and I commend the justices in the majority for having the courage of their convictions."

Pence said the 6-3 decision, which overturned 50 years of precedent, "righted a historic wrong."

He continued, "Having been given this second chance for Life, we must not rest and must not relent until the sanctity of life is restored to the center of American law in every state in the land.”

The former vice president has been a proponent of anti-abortion laws for years and has called numerous times on the court to overturn the decision.