5 Things to Know This Morning

Nov. 23, 2012— -- Your look at the five biggest and most buzz-worthy stories of the morning.

1. Black Friday Madness Begins

Black Friday shopping is underway as hoards of shoppers flood the nation's retailers.

2. 2 Dead, Dozens Hurt in 100-Car Pileup

Two people died and more than 80 people were injured on Thursday when at least 100 vehicles collided on Interstate 10 in Southeast Texas. Intense fog is thought to be the blame for the accident.

3. Future of Gaza Blockade Uncertain

Israeli leaders flew to Cairo yesterday for talks on easing a blockade in Gaza, but the discussions have left the future of the blockade uncertain.

4. 'Macho' Camacho Is Brain Dead

Former lightweight boxing champion Hector "Macho" Camacho is clinically brain dead, doctors said Thursday. The 50-year-old Camacho was shot as he and a friend sat in car in Puerto Rico on Tuesday night.

5. NFL Highlights From Thanksgiving

In Thanksgiving NFL action, the Houston Texans beat the Detroit Lions in overtime, 34-31. The Washington Redskins outlasted the Dallas Cowboys, 38-31, and the New England Patriots trounced the New York Jets, 49-19.